Researcher Portfolio

 
   

Kupke, Sascha Young

Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society  

 

Researcher Profile

 
Position: Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society
Researcher ID: https://pure.mpg.de/cone/persons/resource/persons185714

External references

 
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Publications

 
  (1 - 25 of 83)
 : Pelz, L., Dogra, T., Marichal-Gallardo, P., Hein, M. D., Hemissi, G., Kupke, S. Y., Genzel, Y., & Reichl, U. (2024). Production of antiviral “OP7 chimera” defective interfering particles free of infectious virus. Applied Microbiology and Biotechnology, 108: 97. doi:10.1007/s00253-023-12959-6. [PubMan] : Pelz, L., Rüdiger, D., Hein, M., Böhme, J., Bälkner, M., Kershaw, O., Marichal-Gallardo, P., Gruber, A., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U. (2023). Engineered defective interfering particles of influenza A virus for antiviral treatment. Talk presented at 33rd Annual Meeting of the Society for Virology (GfV). Vienna (Austria). 2023-03-25 - 2023-03-28. [PubMan] : Rüdiger, D., Opitz, P., Kupke, S. Y., & Reichl, U. (2024). A two-dimensional model to predict coinfection of influenza A virus with defective interfering particles in tissue-like systems. Poster presented at Himmelfahrtstagung on Bioprocess Engineering 2024, Regensburg (Germany). [PubMan] : Piasecka, J., Rüdiger, D., Küchler, J., Kupke, S. Y., & Reichl, U. (2024). Mechanisms of antiviral action of the influenza defective interfering particle “OP7”. Poster presented at 28th ESACT Meeting, Edinburgh (Scotland). [PubMan] : Rüdiger, D., Piasecka, J., Küchler, J., Pontes, C., Laske, T., Kupke, S. Y., & Reichl, U. (2024). Mathematical model calibrated to in vitro data predicts mechanisms of antiviral action of the influenza defective interfering particle “OP7”. iScience, 27(4): 109421. doi:10.1016/j.isci.2024.109421. [PubMan] : Rüdiger, D., Opitz, P., Kupke, S. Y., & Reichl, U. (2024). Predicting the antiviral efficacy of defective interfering particles against influenza virus infection in tissues. Talk presented at KSMB-SMB 2024. Seoul (South Korea). 2024-06-29 - 2024-07-06. [PubMan] : Pelz, L., Dogra, T., Rüdiger, D., Boehme, J., Kershaw, O., Bruder, D., Kupke, S. Y., & Reichl, U. (2023). Defective Interfering Particles of Influenza A Virus As Broad-Spectrum Antivirals. Poster presented at 33rd Annual Meeting of the Society for Virology (GfV), Vienna (Austria). [PubMan] : Pelz, L., Rüdiger, D., Hein, M. D., Böhme, J., Bälkner, M., Kershaw, O., Marichal-Gallardo, P., Gruber, A., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U. (2024). Genetic engineering of Influenza A virus defective interfering particles towards improved antiviral efficacy and potential use as a live vaccine. Talk presented at Vaccine Technology IX. Los Cabos (Mexico). 2024-05-19 - 2024-05-24. [PubMan] : Piasecka, J., Rüdiger, D., Küchler, J., Kupke, S. Y., & Reichl, U. (2023). Mechanisms of antiviral action of the influenza defective interfering particle “OP7”. Poster presented at 33rd Annual Meeting of the Society for Virology (GfV), Vienna (Austria). [PubMan] : Rüdiger, D., Opitz, P., Kupke, S. Y., & Reichl, U. (2024). A two-dimensional model to predict influenza virus and defective interfering particle coinfection in tissue-like systems. Talk presented at 28th ESACT Meeting. Edingburgh (Scotland). 2024-06-23 - 2024-06-26. [PubMan] : Dogra, T., Pelz, L., Rüdiger, D., Hein, M. D., Böhme, J., Bälkner, M., Kershaw, O., Marichal-Gallardo, P., Gruber, A., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U. (2024). Genetically engineered defective interfering particles for antiviral treatment and vaccination. Poster presented at 28th ESACT Meeting, Edingburgh (Scotland). [PubMan] : Piasecka, J., Rüdiger, D., Kupke, S. Y., & Reichl, U. (2023). Reduced transcription of the mutated genomic segment 7 of the novel “OP7” influenza defective interfering particle intended for use as an antiviral. Poster presented at 8th European Congress of Virology, Gdańsk (Poland). [PubMan] : Dogra, T., Pelz, L., Rüdiger, D., Hein, M. D., Baelkner, M., Julia D. Boehme, J. D., Marichal-Gallardo, P., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U. (2023). Genetically engineered defective interfering particles of influenza A virus for antiviral treatment and vaccination. Poster presented at 32nd Annual Meeting of the Society for Virology (GfV), Ulm (Germany). [PubMan] : Dogra, T., Pelz, L., Rüdiger, D., Hein, M. D., Baelkner, M., Julia D. Boehme, J. D., Marichal-Gallardo, P., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U. (2023). Genetically engineered defective interfering particles of influenza A virus for antiviral treatment and vaccination. Poster presented at 8th European Congress of Virology, Gdańsk (Poland). [PubMan] : Pelz, L., Rüdiger, D., Dogra, T., Alnaji, F. D., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U. (2023). Semi-continuous Propagation of Influenza A Virus and Its Defective Interfering Particles: Analyzing the Dynamic Competition To Select Candidates for Antiviral Therapy. Talk presented at Vir-AI-DIP Workshop. Hamburg (Germany). 2023-07-18 - 2023-07-20. [PubMan] : Hein, M. D., Kazenmaier, D., van Heuvel, Y., Dogra, T., Cattaneo, M., Kupke, S. Y., Stitz, J., Genzel, Y., & Reichl, U. (2023). Production of retroviral vectors in continuous high cell density culture. Applied Microbiology and Biotechnology, 107, 5947-5961. doi:10.1007/s00253-023-12689-9. [PubMan] : Dogra, T., Pelz, L., Rüdiger, D., Kupke, S. Y., & Reichl, U. (2023). Reverse genetics for Influenza a virus to generate genetically engineered defective interfering particles for antiviral treatment and vaccination. Talk presented at Vir-AI-DIP Workshop. Hamburg (Germany). 2023-07-18 - 2023-07-19. [PubMan] : Pelz, L., Piagnani, E., Marsall, P., Wynserski, N., Hein, M. D., Marichal-Gallardo, P., Kupke, S. Y., & Reichl, U. (2023). Broad-Spectrum Antiviral Activity of Influenza A Defective Interfering Particles against Respiratory Syncytial, Yellow Fever, and Zika Virus Replication In Vitro. Viruses, 15(9): 1872. doi:10.3390/v15091872. [PubMan] : Dogra, T., Pelz, L., Boehme, J. D., Baelkner, M., Kershaw, O., Marichal-Gallardo, P., Gruber, A. D., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U. (2023). Genetically engineered defective interfering particles of influenza A virus for antiviral treatment and vaccination. Talk presented at 17th Vaccine Congress. Glasgow (Scotland). 2023-09-24 - 2023-09-27. [PubMan] : Küchler, J., Opitz, P., Kupke, S. Y., Genzel, Y., Benndorf, D., & Reichl, U. (2023). Absolute quantification of influenza A virus proteins during single-round replication in vaccine producer cell lines. Poster presented at 16th PEACe (Protein Expression in Animal Cells) Conference, Sitges (Spain). [PubMan] : Pelz, L., Genzel, Y., Kupke, S. Y., & Reichl, U. (2023). In-depth characterization and cell culture-based production of influenza A virus defective interfering particles. Talk presented at ACTIP fellowship session. Dublin (Ireland). 2023-10-11 - 2023-10-13. [PubMan] : Rüdiger, D., Pelz, L., Hein, M. D., Kupke, S. Y., & Reichl, U. (2023). Multiscale model of influenza A virus and defective interfering particle co-infection in animal cell culture. Talk presented at Vir-AI-DIP Workshop. Hamburg (Germany). 2023-07-18 - 2023-07-19. [PubMan] : Pelz, L., Dogra, T., Boehme, J., Marichal-Gallardo, P., Hein, M. D., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U. (2023). A Scalable High-Yield Process for Production of Influenza A Virus Defective Interfering Particles and In Vivo Studies. Poster presented at Himmelfahrtstagung on Bioprocess Engineering 2023, Weimar (Germany). [PubMan] : Dogra, T., Pelz, L., Boehme, J. D., Küchler, J., Kershaw, O., Marichal-Gallardo, P., Baelkner, M., Hein, M. D., Gruber, A. D., Benndorf, D., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U. (2023). Generation of “OP7 chimera” defective interfering influenza A particle preparations free of infectious virus that show antiviral efficacy in mice. Scientific Reports, 13: 20936. doi:10.1038/s41598-023-47547-1. [PubMan] : Bälkner, M., Jeron, A., Volckmar, J., Pelz, L., Dogra, T., Kupke, S. Y., & Bruder, D. (2023). Characterization of the local innate immune response after mucosal application of IAV Defective Interfering Particles. European Journal of Immunology, 53(2): P339. doi:10.1002/eji.202370300. [PubMan]