Researcher Portfolio

 
   

Alberti, Simon

Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society  

 

Researcher Profile

 
Position: Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society
Researcher ID: https://pure.mpg.de/cone/persons/resource/persons218962

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Publications

 
  (1 - 25 of 82)
 : Chow, C. F. W., Lenz, S., Scheremetjew, M., Ghosh, S., Richter, D., Jegers, C., Appen, A. v., Alberti, S., & Toth-Petroczy, A. (2025). SHARK-capture identifies functional motifs in intrinsically disordered protein regions. Protein science: a publication of the Protein Society, 34(4): e70091. doi:10.1002/pro.70091. [PubMan] : Verde, E. M., Antoniani, F., Mediani, L., Secco, V., Crotti, S., Ferrara, M. C., Vinet, J., Sergeeva, A., Yan, X., Hoege, C., Stuani, C., Paron, F., Kao, T.-T., Shrivastava, R., Polanowska, J., Bailly, A., Rosa, A., Aronica, E., Goswami, A., Shneider, N., Hyman, A., Buratti, E., Xirodimas, D., Franzmann, T., Alberti, S., & Carra, S. (2025). SUMO2/3 conjugation of TDP-43 protects against aggregation. Science advances, 11(8): 2475. doi:10.1126/sciadv.adq2475. [PubMan] : Beck, T., Linden, L.-M.-v.-d., Borcherds, W. M., Kim, K., Schlüßler, R., Müller, P., Franzmann, T., Möckel, C., Goswami, R., Leaver, M., Mittag, T., Alberti, S., & Guck, J. (2024). Optical characterization of molecular interaction strength in protein condensates. Molecular biology of the cell, 35(12): ar154. doi:10.1091/mbc.E24-03-0128. [PubMan] : Xu, S., Gierisch, M. E., Barchi, E., Poser, I., Alberti, S., Salomons, F. A., & Dantuma, N. P. (2024). Chemical inhibition of the integrated stress response impairs the ubiquitin-proteasome system. Communications biology, 7(1): 1282. doi:10.1038/s42003-024-06974-0. [PubMan] : Altamirano, C. D., Kang, M.-K., Jordan, M. A., Borianne, T., Dilmen, I., Gnädig, M., Appen, A. v., Honigmann, A., Franzmann, T., & Alberti, S. (2024). eIF4F is a thermo-sensing regulatory node in the translational heat shock response. Molecular cell, 84(9), 1727-1741. doi:10.1016/j.molcel.2024.02.038. [PubMan] : Chappidi, N., Quail, T., Doll, S., Vogel, L. T., Aleksandrov, R., Felekyan, S., Kühnemuth, R., Stoynov, S., Seidel, C. A. M., Brugués, J., Jahnel, M., Franzmann, T., & Alberti, S. (2024). PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends. Cell, 187(4), 945-961. doi:10.1016/j.cell.2024.01.015. [PubMan] : Choudhary, D., Mediani, L., Avellaneda, M., Bjarnason, S., Alberti, S., Boczek, E., Heidarsson, P. O., Mossa, A., Carra, S., Tans, S. J., & Cecconi, C. (2023). Human Small Heat Shock Protein B8 Inhibits Protein Aggregation without Affecting the Native Folding Process. Journal of the American Chemical Society, 145(28), 15188-15196. doi:10.1021/jacs.3c02022. [PubMan] : Xu, S., Gierisch, M. E., Schellhaus, A. K., Poser, I., Alberti, S., Salomons, F. A., & Dantuma, N. P. (2023). Cytosolic stress granules relieve the ubiquitin-proteasome system in the nuclear compartment. The EMBO journal, 42(3): e111802. doi:10.15252/embj.2022111802. [PubMan] : Arter, W. E., Qi, R., Erkamp, N. A., Krainer, G., Didi, K., Welsh, T. J., Acker, J., Nixon-Abell, J., Qamar, S., Guillén-Boixet, J., Franzmann, T., Kuster, D., Hyman, A., Borodavka, A., George-Hyslop, P. S., Alberti, S., & Knowles, T. P. J. (2022). Biomolecular condensate phase diagrams with a combinatorial microdroplet platform. Nature communications, 13(1): 7845. doi:10.1038/s41467-022-35265-7. [PubMan] : Maharana, S., Kretschmer, S., Hunger, S., Yan, X., Kuster, D., Traikov, S., Zillinger, T., Gentzel, M., Elangovan, S., Dasgupta, P., Chappidi, N., Lucas, N., Maser, K. I., Maatz, H., Rapp, A., Marchand, V., Chang, Y.-T., Motorin, Y., Hubner, N., Hartmann, G., Hyman, A., Alberti, S., & Lee-Kirsch, M. A. (2022). SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA. Molecular cell, 82(19), 3712-3728. doi:10.1016/j.molcel.2022.08.031. [PubMan] : Kar, M., Dar, F., Welsh, T. J., Vogel, L. T., Kühnemuth, R., Majumdar, A., Krainer, G., Franzmann, T., Alberti, S., Seidel, C. A. M., Knowles, T. P. J., Hyman, A., & Pappu, R. V. (2022). Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutions. Proceedings of the National Academy of Sciences of the United States of America, 119(28): e2202222119. doi:10.1073/pnas.2202222119. [PubMan] : Welsh, T. J., Krainer, G., Espinosa, J. R., Joseph, J. A., Sridhar, A., Jahnel, M., Arter, W. E., Saar, K., Alberti, S., Collepardo-Guevara, R., & Knowles, T. P. J. (2022). Surface Electrostatics Govern the Emulsion Stability of Biomolecular Condensates. Nano letters, 22(2), 612-621. doi:10.1021/acs.nanolett.1c03138. [PubMan] : Tiago, T., Hummel, B., Morelli, F. F., Basile, V., Vinet, J., Galli, V., Mediani, L., Antoniani, F., Pomella, S., Cassandri, M., Garone, M. G., Silvestri, B., Cimino, M., Cenacchi, G., Costa, R., Mouly, V., Poser, I., Yeger-Lotem, E., Rosa, A., Alberti, S., Rota, R., Ben-Zvi, A., Sawarkar, R., & Carra, S. (2021). Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptor. Cell death & disease, 12(5): 452. doi:10.1038/s41419-021-03737-1. [PubMan] : Evers, T. M. J., Holt, L. J., Alberti, S., & Mashaghi, A. (2021). Reciprocal regulation of cellular mechanics and metabolism. Nature metabolism, 3(4), 456-468. doi:10.1038/s42255-021-00384-w. [PubMan] : Krainer, G., Welsh, T. J., Joseph, J. A., Espinosa, J. R., Wittmann, S., Csilléry, E. d., Sridhar, A., Toprakcioglu, Z., Gudiškytė, G., Czekalska, M. A., Arter, W. E., Guillén-Boixet, J., Franzmann, T., Qamar, S., George-Hyslop, P. S., Hyman, A., Collepardo-Guevara, R., Alberti, S., & Knowles, T. P. J. (2021). Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions. Nature communications, 12(1): 1085. doi:10.1038/s41467-021-21181-9. [PubMan] : Alberti, S., & Hyman, A. (2021). Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing. Nature reviews. Molecular cell biology, 22(3), 196-213. doi:10.1038/s41580-020-00326-6. [PubMan] : Mediani, L., Galli, V., Carrà, A. D., Bigi, I., Vinet, J., Ganassi, M., Antoniani, F., Tiago, T., Cimino, M., Mateju, D., Cereda, C., Pansarasa, O., Alberti, S., Mandrioli, J., & Carra, S. (2020). BAG3 and BAG6 differentially affect the dynamics of stress granules by targeting distinct subsets of defective polypeptides released from ribosomes. Cell stress & chaperones, 25(6), 1045-1058. doi:10.1007/s12192-020-01141-w. [PubMan] : Shen, Y., Ruggeri, F. S., Vigolo, D., Kamada, A., Qamar, S., Levin, A., Iserman, C., Alberti, S., George-Hyslop, P. S., & Knowles, T. P. J. (2020). Biomolecular condensates undergo a generic shear-mediated liquid-to-solid transition. Nature nanotechnology, 15(10), 841-847. doi:10.1038/s41565-020-0731-4. [PubMan] : Nüske, E., Marini, G., Richter, D., Leng, W., Bogdanova, A., Franzmann, T., Pigino, G., & Alberti, S. (2020). Filament formation by the translation factor eIF2B regulates protein synthesis in starved cells. Biology open, 9(7): bio.046391. doi:10.1242/bio.046391. [PubMan] : Marini, G., Nüske, E., Leng, W., Alberti, S., & Pigino, G. (2020). Reorganization of budding yeast cytoplasm upon energy depletion. Molecular biology of the cell, 31(12), 1232-1245. doi:10.1091/mbc.E20-02-0125. [PubMan] : Iserman, C., Altamirano, C. D., Jegers, C., Friedrich, U., Zarin, T., Fritsch, A., Mittasch, M., Domingues, A., Hersemann, L., Jahnel, M., Richter, D., Guenther, U.-P., Hentze, M. W., Moses, A. M., Hyman, A., Kramer, G., Kreysing, M., Franzmann, T., & Alberti, S. (2020). Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production. Cell, 181(4), 818-831. doi:10.1016/j.cell.2020.04.009. [PubMan] : Guillén-Boixet, J., Kopach, A., Holehouse, A. S., Wittmann, S., Jahnel, M., Schlüßler, R., Kim, K., Trussina, I., Wang, J., Mateju, D., Poser, I., Maharana, S., Ruer-Gruß, M., Richter, D., Zhang, X., Chang, Y.-T., Guck, J., Honigmann, A., Mahamid, J., Hyman, A., Pappu, R. V., Alberti, S., & Franzmann, T. (2020). RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation. Cell, 181(2), 346-361. doi:10.1016/j.cell.2020.03.049. [PubMan] : Mandrioli, J., Mediani, L., Alberti, S., & Carra, S. (2020). ALS and FTD: Where RNA metabolism meets protein quality control. Seminars in cell & developmental biology, 99, 183-192. doi:10.1016/j.semcdb.2019.06.003. [PubMan] : Alberti, S., & Dormann, D. (2019). Liquid-Liquid Phase Separation in Disease. Annual review of genetics, 53, 171-194. doi:10.1146/annurev-genet-112618-043527. [PubMan] : Mediani, L., Guillén-Boixet, J., Vinet, J., Franzmann, T., Bigi, I., Mateju, D., Carrà, A. D., Morelli, F. F., Tiago, T., Poser, I., Alberti, S., & Carra, S. (2019). Defective ribosomal products challenge nuclear function by impairing nuclear condensate dynamics and immobilizing ubiquitin. The EMBO journal, 38(15): e101341. doi:10.15252/embj.2018101341. [PubMan]