Researcher Portfolio

Wettschureck, Nina

Pharmacology, Max Planck Institute for Heart and Lung Research, Max Planck Society

Researcher Profile

Position: Pharmacology, Max Planck Institute for Heart and Lung Research, Max Planck Society

Researcher ID: https://pure.mpg.de/cone/persons/resource/persons224211

External references

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Publications

(1 - 25 of 41)

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: Yoshida, T., Yoshida, S., Inukai, K., Kato, K., Yura, Y., Hattori, T., Taki, K., Enomoto, A., Ohashi, K., Okumura, T., Ouchi, N., Kawase, H., Wettschureck, N., Offermanns, S., Murohara, T., & Takefuji, M. (2024). ALPK2 prevents cardiac diastolic dysfunction in heart failure with preserved ejection fraction. FASEB JOURNAL, 38(22): e70192. doi:10.1096/fj.202402103R. [PubMan] : Alnouri, M. W., Roquid, K. A., Bonnavion, R., Cho, H., Heering, J., Kwon, J., Jaeger, Y., Wang, S., Guenther, S., Wettschureck, N., Geisslingerb, G., Gurke, R., Mueller, C. E., Proschak, E., & Offermanns, S. (2024). SPMs exert anti- inflammatory and pro- resolving effects through positive allosteric modulation of the prostaglandin EP4 receptor. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 121(41): e2407130121. doi:10.1073/pnas.2407130121. [PubMan] : Yoshida, S., Yoshida, T., Inukai, K., Kato, K., Yura, Y., Hattori, T., Enomoto, A., Ohashi, K., Okumura, T., Ouchi, N., Kawase, H., Wettschureck, N., Offermanns, S., Murohara, T., & Takefuji, M. (2024). Protein kinase N promotes cardiac fibrosis in heart failure by fibroblast-to-myofibroblast conversion. NATURE COMMUNICATIONS, 15(1): 7638. doi:10.1038/s41467-024-52068-0. [PubMan] : Peng, Y., Du, J., Li, R., Guenther, S., Wettschureck, N., Offermanns, S., Wang, Y., Schneider, A., & Braun, T. (2024). RhoA-mediated G₁₂-G₁₃ signaling maintains muscle stem cell quiescence and prevents stem cell loss. CELL DISCOVERY, 10(1): 76. doi:10.1038/s41421-024-00696-7. [PubMan] : Wang, T., Shao, J., Shamit, K., Alnouri, M. W., Carvalho, J., Guenther, S., Krasel, C., Murphy, K. T., Buenemann, M., Offermanns, S., & Wettschureck, N. (2024). Orphan GPCR GPRC5C Facilitates Angiotensin II-Induced Smooth Muscle Contraction. CIRCULATION RESEARCH, 134(10), 1259-1275. doi:10.1161/CIRCRESAHA.123.323752. [PubMan] : Tamiato, A., Tombor, L. S., Fischer, A., Muhly-Reinholz, M., Vanicek, L. R., Togru, B. N., Neitz, J., Glaser, S. F., Merten, M., Morales, D. R., Kwon, J., Klatt, S., Schumacher, B., Guenther, S., Abplanalp, W. T., John, D., Fleming, I., Wettschureck, N., Dimmeler, S., & Luxaen, G. (2024). Age-Dependent RGS5 Loss in Pericytes Induces Cardiac Dysfunction and Fibrosis. CIRCULATION RESEARCH, 134(10), 1240-1255. doi:10.1161/CIRCRESAHA.123.324183. [PubMan] : Kurz, M., Ulrich, M., Bittner, A., Scharf, M. M., Shao, J., Wallenstein, I., Lemoine, H., Wettschureck, N., Kolb, P., & Buenemann, M. (2023). EP4 Receptor Conformation Sensor Suited for Ligand Screening and Imaging of Extracellular Prostaglandins. MOLECULAR PHARMACOLOGY, 104(3), 80-91. doi:10.1124/molpharm.122.000648. [PubMan] : Li, R., Shao, J., Jin, Y. J., Haruya, K., Ong, Y. T., Troidl, K., Quan, Q., Wang, L., Bonnavion, R., Wietelmann, A., Helmbacher, F., Potente, M., Graumann, J., Wettschureck, N., & Offermanns, S. (2023). Endothelial FAT1 inhibits angiogenesis by controlling YAP/TAZ protein degradation via E3 ligase MIB2. NATURE COMMUNICATIONS, 14(1): 1980. doi:10.1038/s41467-023-37671-x. [PubMan] : Wang, S., Wang, B., Shi, Y., Moeller, T., Stegmeyer I, R., Strilic, B., Li, T., Yuan, Z., Wang, C., Wettschureck, N., Vestweber, D., & Offermanns, S. (2022). Mechanosensation by endothelial PIEZO1 is required for leukocyte diapedesis. BLOOD, 140(3), 171-183. doi:10.1182/blood.2021014614. [PubMan] : Wang, S., Wang, B., Shi, Y., Moller, T., Stegmeyer, R. I., Strilic, B., Li, T., Yuan, Z., Wang, C., Wettschureck, N., Vestweber, D., & Offermanns, S. (2022). Mechanosensation by endothelial PIEZO1 is required for leukocyte diapedesis. Blood. doi:10.1182/blood.2021014614. [PubMan] : Gurusamy, M., Tischner, D., Shao, J., Klatt, S., Zukunft, S., Bonnavion, R., Guenther, S., Siebenbrodt, K., Kestner, R.-I., Kuhlmann, T., Fleming, I., Offermanns, S., & Wettschureck, N. (2021). G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators. NATURE COMMUNICATIONS, 12(1): 6798. doi:10.1038/s41467-021-26882-9. [PubMan] : Ishihama, S., Yoshida, S., Yoshida, T., Mori, Y., Ouchi, N., Eguchi, S., Sakaguchi, T., Tsuda, T., Kato, K., Shimizu, Y., Ohashi, K., Okumura, T., Bando, Y. K., Yagyu, H., Wettschureck, N., Kubota, N., Offermanns, S., Kadowaki, T., Murohara, T., & Takefuji, M. (2021). LPL/AQP7/GPD2 promotes glycerol metabolism under hypoxia and prevents cardiac dysfunction during ischemia. FASEB JOURNAL, 35(12): e22048. doi:10.1096/fj.202100882R. [PubMan] : Jin, Y.-J., Chennupati, R., Li, R., Liang, G., Wang, S., Iring, A., Graumann, J., Wettschureck, N., & Offermanns, S. (2021). Protein kinase N2 mediates flow-induced endothelial NOS activation and vascular tone regulation. JOURNAL OF CLINICAL INVESTIGATION, 131(21): e145734. doi:10.1172/JCI145734. [PubMan] : Demirel, E., Arnold, C., Garg, J., Jaeger, M. A., Sticht, C., Li, R., Kuk, H., Wettschureck, N., Hecker, M., & Korff, T. (2021). RGS5 Attenuates Baseline Activity of ERK1/2 and Promotes Growth Arrest of Vascular Smooth Muscle Cells. CELLS, 10(7): 1748. doi:10.3390/cells10071748. [PubMan] : Xu, L., Wettschureck, N., Bai, Y., Yuan, Z., & Wang, S. (2021). Myofibroblast YAP/TAZ is dispensable for liver fibrosis in mice. JOURNAL OF HEPATOLOGY, 75(1), 238-241. doi:10.1016/j.jhep.2021.02.026. [PubMan] : Carvalho, J., Chennupati, R., Li, R., Guenther, S., Kaur, H., Zhao, W., Tonack, S., Kurz, M., Moesslein, N., Buenemann, M., Offermanns, S., & Wettschureck, N. (2020). Orphan G Protein-Coupled Receptor GPRC5B Controls Smooth Muscle Contractility and Differentiation by Inhibiting Prostacyclin Receptor Signaling. CIRCULATION, 141(14), 1168-1183. doi:10.1161/CIRCULATIONAHA.119.043703. [PubMan] : van den Bos, E., Ambrosy, B., Horsthemke, M., Walbaum, S., Bachg, A. C., Wettschureck, N., Innamorati, G., Wilkie, T. M., & Hanley, P. J. (2020). Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor?mediated chemotaxis. JOURNAL OF BIOLOGICAL CHEMISTRY, 295(22), 7726-7742. doi:10.1074/jbc.RA119.011984. [PubMan] : Wang, S., Cao, S., Arhatte, M., Li, D., Shi, Y., Kurz, S., Hu, J., Wang, L., Shao, J., Atzberger, A., Wang, Z., Wang, C., Zang, W., Fleming, I., Wettschureck, N., Honore, E., & Offermanns, S. (2020). Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice. NATURE COMMUNICATIONS, 11(1). doi:10.1038/s41467-020-16026-w. [PubMan] : Sakaguchi, T., Takefuji, M., Wettschureck, N., Hamaguchi, T., Amano, M., Kato, K., Tsuda, T., Eguchi, S., Ishihama, S., Mori, Y., Yura, Y., Yoshida, T., Unno, K., Okumura, T., Ishii, H., Shimizu, Y., Bando, Y. K., Ohashi, K., Ouchi, N., Enomoto, A., Offermanns, S., Kaibuchi, K., & Murohara, T. (2019). Protein Kinase N Promotes Stress-Induced Cardiac Dysfunction Through Phosphorylation of Myocardin-Related Transcription Factor A and Disruption of Its Interaction With Actin. CIRCULATION, 140(21), 1737-1752. doi:10.1161/CIRCULATIONAHA.119.041019. [PubMan] : Chennupati, R., Wirth, A., Favre, J., Li, R., Bonnavion, R., Jin, Y.-J., Wietelmann, A., Schweda, F., Wettschureck, N., Henrion, D., & Offermanns, S. (2019). Myogenic vasoconstriction requires G(12)/G(13) and LARG to maintain local and systemic vascular resistance. ELIFE, 8: e49374. doi:10.7554/eLife.49374. [PubMan] : Wettschureck, N., Strilic, B., & Offermanns, S. (2019). PASSING THE VASCULAR BARRIER: ENDOTHELIAL SIGNALING PROCESSES CONTROLLING EXTRAVASATION. PHYSIOLOGICAL REVIEWS, 99(3), 1467-1525. doi:10.1152/physrev.00037.2018. [PubMan] : Iring, A., Jin, Y.-J., Albarran-Juarez, J., Siragusa, M., Wang, S., Dancs, P. T., Nakayama, A., Tonack, S., Chen, M., Kuenne, C., Sokol, A. M., Guenther, S., Martinez, A., Fleming, I., Wettschureck, N., Graumann, J., Weinstein, L. S., & Offermanns, S. (2019). Shear stress-induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure. JOURNAL OF CLINICAL INVESTIGATION, 129(7), 2775-2791. doi:10.1172/JCI123825. [PubMan] : Albarran-Juarez, J., Iring, A., Wang, S., Joseph, S., Grimm, M., Strilic, B., Wettschureck, N., Althoff, T. F., & Offermanns, S. (2018). Piezo1 and G(q)/G(11) promote endothelial inflammation depending on flow pattern and integrin activation. JOURNAL OF EXPERIMENTAL MEDICINE, 215(10), 2655-2672. doi:10.1084/jem.20180483. [PubMan] : Rodiger, M., Werno, M. W., Wilhelmi, I., Baumeier, C., Hesse, D., Wettschureck, N., Offermanns, S., Song, K., Krauss, M., & Schuermann, A. (2018). Adiponectin release and insulin receptor targeting share trans-Golgi-dependent endosomal trafficking routes. MOLECULAR METABOLISM, 8, 167-179. doi:10.1016/j.molmet.2017.11.011. [PubMan] : Breuer, J., Herich, S., Schneider-Hohendorf, T., Chasan I, A., Wettschureck, N., Gross, C. C., Loser, K., Zarbock, A., Roth, J., Klotz, L., Wiendl, H., & Schwab, N. (2018). Dual action by fumaric acid esters synergistically reduces adhesion to human endothelium. MULTIPLE SCLEROSIS JOURNAL, 24(14), 1871-1882. doi:10.1177/1352458517735189. [PubMan]