Researcher Portfolio
Steiger, Mara
Computational Genomics (Helene Kretzmer), Dept. of Genome Regulation (Head: Alexander Meissner), Max Planck Institute for Molecular Genetics, Max Planck Society
Researcher Profile
Position: Computational Genomics (Helene Kretzmer), Dept. of Genome Regulation (Head: Alexander Meissner), Max Planck Institute for Molecular Genetics, Max Planck Society
Additional IDs: ORCID:
https://orcid.org/0000-0002-3747-685X
Researcher ID: https://pure.mpg.de/cone/persons/resource/persons247274
Publications
(1 - 25 of 29)
: Iyer, D. P., Khoei, H. H., van der Weijden, V. A., Kagawa, H., Pradhan, S. J., Novatchkova, M., McCarthy, A., Rayon, T., Simon, C. S., Dunkel, I., Wamaitha, S. E., Elder, K., Snell, P., Christie, L., Schulz, E. G., Niakan, K. K., Rivron, N., & Bulut-Karslioglu, A. (2024). mTOR activity paces human blastocyst stage developmental progression. Cell, 187(23), 6566-6583. doi:10.1016/j.cell.2024.08.048. [PubMan] : Mutzel, V., Schwämmle, T., Oeverdieck, S., Librenjak, L., Boesen, B., Bothe, M., Gjaltema, R. A. F., Dunkel, I., Noviello, G., & Schulz, E. G. (2024). Antisense transcription can induce expression memory via stable promoter repression. bioRxiv. doi:10.1101/2024.03.06.583761. [PubMan] : Ravid Lustig, L., Sampath Kumar, A., Schwämmle, T., Dunkel, I., Noviello, G., Limberg, E., Weigert, R., Pacini, G., Buschow, R., Ghauri, A., Stötzel, M., Wittler, L., Meissner, A., & Schulz, E. G. (2023). GATA transcription factors drive initial Xist upregulation after fertilization through direct activation of long-range enhancers. Nature Cell Biology, 25(11), 1704-1715. doi:10.1038/s41556-023-01266-x. [PubMan] : de Sousa, J. A., Wong, C.-W., Dunkel, I., Owens, T., Voigt, P., Hodgson, A., Baker, D., Schulz, E. G., Reik, W., Smith, A., Rostovskaya, M., & von Meyenn, F. (2023). Epigenetic dynamics during capacitation of naïve human pluripotent stem cells. Science Advances, 9(39): eadg1936. doi:10.1126/sciadv.adg1936. [PubMan] : Sultana, Z., Dorel, M., Klinger, B., Sieber, A., Dunkel, I., Blüthgen, N., & Schulz, E. G. (2023). Modeling unveils sex differences of signaling networks in mouse embryonic stem cells. Molecular Systems Biology, 19(11): e11510. doi:10.15252/msb.202211510. [PubMan] : Iyer, D. P., van der Weijden, V. A., Khoei, H. H., McCarthy, A., Rayon, T., Simon, C. S., Dunkel, I., Wamaitha, S. E., Elder, K., Snell, P., Christie, L., Schulz, E. G., Niakan, K. K., Rivron, N., & Bulut-Karslioglu, A. (2023). Delay of human early development via in vitro diapause. bioRxiv, 2023. doi:10.1101/2023.05.29.541316. [PubMan] : Ravid-Lustig, L., Sampath Kumar, A., Schwämmle, T., Dunkel, I., Noviello, G., Weigert, R., Pacini, G., Buschow, R., Ghauri, A., Stötzel, M., Wittler, L., Meissner, A., & Schulz, E. G. (2022). GATA transcription factors drive initial Xist upregulation after fertilization through direct activation of a distal enhancer element. bioRxiv. doi:10.1101/2022.08.02.502458. [PubMan] : Gjaltema, R. A. F., Schwämmle, T., Kautz, P., Robson, M., Schöpflin, R., Ravid Lustig, L., Brandenburg, L., Dunkel, I., Vechiatto, C., Ntini, E., Mutzel, V., Schmiedel, V., Marsico, A., Mundlos, S., & Schulz, E. G. (2022). Distal and proximal cis-regulatory elements sense X-chromosomal dosage and developmental state at the Xist locus. Molecular Cell, 82(1), 190-208. doi:10.1016/j.molcel.2021.11.023. [PubMan] : Pacini, G., Dunkel, I., Mages, N., Mutzel, V., Timmermann, B., Marsico, A., & Schulz, E. G. (2021). Integrated analysis of Xist upregulation and X-chromosome inactivation with single-cell and single-allele resolution. Nature Communications, 12(1): 3638. doi:0.1038/s41467-021-23643-6. [PubMan] : Genolet, O., Monaco, A. A., Dunkel, I., Boettcher, M., & Schulz, E. G. (2021). Identification of X-chromosomal genes that drive global X-dosage effects in mammals. Genome Biology, 22: 110. doi:10.1186/s13059-021-02321-2. [PubMan] : Sahu, A., Li, N., Dunkel, I., & Chung, H. (2020). EPIGENE: genome-wide transcription unit annotation using a multivariate probabilistic model of histone modifications. Epigenetics & Chromatin, 13: 13:20. doi:10.1186/s13072-020-00341-z. [PubMan] : Grunert, M., Appelt, S., Dunkel, I., Berger, F., & Sperling, S. R. (2019). Altered microRNA and target gene expression related to Tetralogy of Fallot. Scientific Reports, 9(1): 19063. doi:10.1038/s41598-019-55570-4. [PubMan] : Barros de Andrade e Sousa, L., Jonkers, I., Syx, L., Dunkel, I., Chaumeil, J., Picard, C., Foret, B., Chen, C.-J., Lis, J. T., Heard, E., Schulz, E. G., & Marsico, A. (2019). Kinetics of Xist-induced gene silencing can be predicted from combinations of epigenetic and genomic features. Genome Research, 29(7), 1087-1099. doi:10.1101/gr.245027.118. [PubMan] : Mutzel, V., Okamoto, I., Dunkel, I., Saitou, M., Giorgetti, L., Heard, E., & Schulz, E. G. (2019). A symmetric toggle switch explains the onset of random X inactivation in different mammals. Nature Structural and Molecular Biology, 26(5), 350-360. doi:10.1038/s41594-019-0214-1. [PubMan] : Mutzel, V., Okamoto, I., Dunkel, I., Saitou, M., Giorgetti, L., Heard, E., & Schulz, E. G. (2017). Two coupled feedback loops explain random mono-allelic Xist upregulation at the onset of X-chromosome inactivation. bioRxiv: the preprint server for biology, 2017, 1-54. doi:10.1101/204909. [PubMan] : Kinkley, S., Helmuth, J., Polansky, J. K., Dunkel, I., Gasparoni, G., Fröhler, S., Chen, W., Walter, J., Hamann, A., & Chung, H.-R. (2016). reChIP-seq reveals widespread bivalency of H3K4me3 and H3K27me3 in CD4+ memory T-Cells. Nature Communications, 7: 7:12514. doi:10.1038/ncomms12514. [PubMan] : Chung, H.-R., Xu, C., Fuchs, A., Mund, A., Lange, M., Staege, H., Schubert, T., Bian, C., Dunkel, I., Eberharter, A., Regnard, C., Klinker, H., Meierhofer, D., Cozzuto, L., Winterpracht, A., Di Croce, L., Min, J., Will, H., & Kinkley, S. (2016). PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3. eLife, 5: 5:e10607. doi:10.7554/eLife.10607. [PubMan] : Cui, H., Schlesinger, J., Bansal, V., Dunkel, I., Meierhofer, D., & Rickert-Sperling, S. (2014). 5Regulation of myogenesis via kinase driven activation of DPF3a, a BAF complex member and its interaction with transcription repressor HEY1. Cardiovascular Research, 103(Suppl 1): S 1. doi:10.1093/cvr/cvu074.1. [PubMan] : Grunert, M., Dorn, C., Schueler, M., Dunkel, I., Schlesinger, J., Mebus, S., Alexi-Meskishvili, V., Perrot, A., Wassilew, K., Timmermann, B., Hetzer, R., Berger, F., & Sperling, S. R. (2014). Rare and Private Variations in Neural Crest, Apoptosis and Sarcomere Genes Define the Polygenic Background of Isolated Tetralogy of Fallot. Human Molecular Genetics, 23(12), 3115-3128. doi:10.1093/hmg/ddu021. [PubMan] : Schlesinger, J., Schueler, M., Grunert, M., Fischer, J. J., Zhang, Q., Krueger, T., Lange, M., Tönjes, M., Dunkel, I., & Sperling, S. (2011). The Cardiac Transcription Network Modulated by Gata4, Mef2a, Nkx2.5, Srf, Histone Modifications, and MircoRNAs. PLoS Genetics, 7(2): e1001313. doi:10.1371/journal.pgen1001313. [PubMan] : Chung, H.-R., Dunkel, I., Heise, F., Linke, C., Krobitsch, S., Ehrenhofer-Murray, A. E., Sperling, S. R., & Vingron, M. (2010). The effect of MNase on nucleosome positioning data. PLoS ONE, 5(12), e15754-e15754. doi:10.1371/journal.pone.0015754. [PubMan] : Schlesinger, J., Tönjes, M., Schueler, M., Zhang, Q., Dunkel, I., & Sperling, S. R. (2010). Evaluation of the LightCycler(R) 1536 Instrument for high-throughput quantitative real-time PCR. Methods, 50(4), S19-S22. doi:10.1016/j.ymeth.2010.01.007. [PubMan] : Schlesinger, J., Tönjes, M., Schueler, M., Zhang, Q., Dunkel, I., & Sperling, S. R. (2010). Evaluation of the LightCycler(R) 1536 Instrument for high-throughput quantitative real-time PCR. Methods, 50(4), S19-S22. doi:10.1016/j.ymeth.2010.01.007. [PubMan] : Lange, M., Kaynak, B., Forster, U. B., Tönjes, M., Fischer, J. J., Grimm, C., Schlesinger, J., Just, S., Dunkel, I., Krueger, T., Mebus, S., Lehrach, H., Lurz, R., Gobom, J., Rottbauer, W., Abdelilah-Seyfried, S., & Sperling, S. (2008). Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex. Genes and Development, 22(17), 2370-2384. doi:10.1101/gad.471408. [PubMan] : Lange, M., Kaynak, B., Forster, U. B., Tönjes, M., Fischer, J. J., Grimm, C., Schlesinger, J., Just, S., Dunkel, I., Krueger, T., Mebus, S., Lehrach, H., Lurz, R., Gobom, J., Rottbauer, W., Abdelilah-Seyfried, S., & Sperling, S. (2008). Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex. Genes and Development, 22(17), 2370-2384. doi:10.1101/gad.471408. [PubMan]