Researcher Portfolio
Groh, Roan René
Department of Molecular Membrane Biology, Max Planck Institute of Biophysics, Max Planck Society
Researcher Profile
Position: Department of Molecular Membrane Biology, Max Planck Institute of Biophysics, Max Planck Society
Researcher ID: https://pure.mpg.de/cone/persons/resource/persons257251
Publications
(1 - 25 of 30)
: Simard, M.-L., Mourier, A., Greaves, L. C., Taylor, R. W., & Stewart, J. (2018). A novel histochemistry assay to assess and quantify focal cytochrome c oxidase deficiency. J Pathol, 245(3), 311-323. doi:10.1002/path.5084. [PubMan] : Kauppila, J. H. K., Bonekamp, N., Mourier, A., Isokallio, M., Just, A., Kauppila, T., Stewart, J., & Larsson, N. (2018). Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res, 46(13), 6642-6669. doi:10.1093/nar/gky456. [PubMan] : Kühl, I., Miranda, M., Atanassov, I., Kuznetsova, I., Hinze, Y., Mourier, A., Filipovska, A., & Larsson, N. (2017). Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals. Elife, 6. doi:10.7554/eLife.30952. [PubMan] : Brandt, T., Mourier, A., Tain, L. S., Partridge, L., Larsson, N.-G., & Kühlbrandt, W. (2017). Changes of mitochondrial ultrastructure and function during ageing in mice and Drosophila. eLife, 6: e24662. doi:10.7554/eLife.24662. [PubMan] : Brandt, T., Mourier, A., Tain, L. S., Partridge, L., Larsson, N., & Kuhlbrandt, W. (2017). Changes of mitochondrial ultrastructure and function during ageing in mice and Drosophila. Elife, 6. doi:10.7554/eLife.24662. [PubMan] : Kauppila, J. H. K., Baines, H. L., Bratic, A., Simard, M.-L., Freyer, C., Mourier, A., Stamp, C., Filograna, R., Larsson, N., Greaves, L. C., & Stewart, J. B. (2016). A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease. Cell Rep, 16(11), 2980-90. doi:10.1016/j.celrep.2016.08.037. [PubMan] : Perez-Perez, R., Lobo-Jarne, T., Milenkovic, D., Mourier, A., Bratic, A., Garcia-Bartolome, A., Fernandez-Vizarra, E., Cadenas, S., Delmiro, A., Garcia-Consuegra, I., Arenas, J., Martin, M. A., Larsson, N., & Ugalde, C. (2016). COX7A2L Is a Mitochondrial Complex III Binding Protein that Stabilizes the III2+IV Supercomplex without Affecting Respirasome Formation. Cell Rep, 16(9), 2387-98. doi:10.1016/j.celrep.2016.07.081. [PubMan] : Kühl, I., Miranda, M., Posse, V., Milenkovic, D., Mourier, A., Siira, S. J., Bonekamp, N., Neumann, U., Filipovska, A., Polosa, P. L., Gustafsson, C. M., & Larsson, N. (2016). POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA. Sci Adv, 2(8), e1600963. doi:10.1126/sciadv.1600963. [PubMan] : Rackham, O., Busch, J. D., Matic, S., Siira, S. J., Kuznetsova, I., Atanassov, I., Ermer, J. A., Shearwood, A. M., Richman, T. R., Stewart, J. B., Mourier, A., Milenkovic, D., Larsson, N., & Filipovska, A. (2016). Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly. Cell Rep, 16(7), 1874-90. doi:10.1016/j.celrep.2016.07.031. [PubMan] : Ramos, E., Larsson, N., & Mourier, A. (2016). Bioenergetic roles of mitochondrial fusion. Biochim Biophys Acta, 1857(8), 1277-83. doi:10.1016/j.bbabio.2016.04.002. [PubMan] : Rackham, O., Busch, J. D., Matic, S., Siira, S., Kuznetsova, I., Atanassov, I., Ermer, J., Shearwood, A.-M.-J., Richman, T., Stewart, J. B., Mourier, A., Milenkovic, D., Larsson, N., & Filipovska, A. (2016). Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly. Cell Reports, 16(7), 1874-1890. doi:http://dx.doi.org/10.1016/j.celrep.2016.07.031. [PubMan] : Kauppila, J. H. K., Baines, H. L., Bratic, A., Simard, M.-L., Freyer, C., Mourier, A., Stamp, C., Filograna, R., Larsson, N., Greaves, L. C., & Stewart, J. B. (2016). A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease. Cell reports, 16(11), 2980-2990. doi:10.1016/j.celrep.2016.08.037. [PubMan] : Kühl, I., Miranda, M., Posse, V., Milenkovic, D., Mourier, A., Siira, S. J., Bonekamp, N. A., Neumann, U., Filipovska, A., Polosa, P. L., Gustafsson, C. M., & Larsson, N. (2016). POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA. Science advances, 2(8), e1600963. doi:10.1126/sciadv.1600963. [PubMan] : Lagouge, M., Mourier, A., Lee, H., Spahr, H., Wai, T., Kukat, C., Ramos, E., Motori, E., Busch, J. D., Siira, S., Kremmer, E., Filipovska, A., & Larsson, N. (2015). SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation. PLoS Genet, 11(8), e1005423. doi:10.1371/journal.pgen.1005423. [PubMan] : Freyer, C., Stranneheim, H., Naess, K., Mourier, A., Felser, A., Maffezzini, C., Lesko, N., Bruhn, H., Engvall, M., Wibom, R., Barbaro, M., Hinze, Y., Magnusson, M., Andeer, R., Zetterstrom, R. H., von Dobeln, U., Wredenberg, A., & Wedell, A. (2015). Rescue of primary ubiquinone deficiency due to a novel COQ7 defect using 2,4-dihydroxybensoic acid. J Med Genet, 52(11), 779-83. doi:10.1136/jmedgenet-2015-102986. [PubMan] : Mourier, A., Motori, E., Brandt, T., Lagouge, M., Atanassov, I., Galinier, A., Rappl, G., Brodesser, S., Hultenby, K., Dieterich, C., & Larsson, N. (2015). Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels. J Cell Biol, 208(4), 429-42. doi:10.1083/jcb.201411100. [PubMan] : Mourier, A., Motori, E., Brandt, T., Lagouge, M., Atanassov, I., Galinier, A., Rappl, G., Brodesser, S., Hultenby, K., Dieterich, C., & Larsson, N.-G. (2015). Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels. The Journal of Cell Biology: JCB, 208(4), 429-442. doi:10.1083/jcb.201411100. [PubMan] : Mourier, A., Matic, S., Ruzzenente, B., Larsson, N., & Milenkovic, D. (2014). The respiratory chain supercomplex organization is independent of COX7a2l isoforms. Cell Metab, 20(6), 1069-75. doi:10.1016/j.cmet.2014.11.005. [PubMan] : Baggio, F., Bratic, A., Mourier, A., Kauppila, T. E. S., Tain, L. S., Kukat, C., Habermann, B., Partridge, L., & Larsson, N. (2014). Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation. Nucleic Acids Res, 42(22), 13920-38. doi:10.1093/nar/gku1132. [PubMan] : Kühl, I., Kukat, C., Ruzzenente, B., Milenkovic, D., Mourier, A., Miranda, M., Koolmeister, C., Falkenberg, M., & Larsson, N. (2014). POLRMT does not transcribe nuclear genes. Nature, 514(7521), E7-11. doi:10.1038/nature13690. [PubMan] : Vernochet, C., Damilano, F., Mourier, A., Bezy, O., Mori, M. A., Smyth, G., Rosenzweig, A., Larsson, N., & Kahn, C. R. (2014). Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications. Faseb j, 28(10), 4408-19. doi:10.1096/fj.14-253971. [PubMan] : Mourier, A., Ruzzenente, B., Brandt, T., Kuhlbrandt, W., & Larsson, N. (2014). Loss of LRPPRC causes ATP synthase deficiency. Hum Mol Genet, 23(10), 2580-92. doi:10.1093/hmg/ddt652. [PubMan] : Ross, J. M., Stewart, J. B., Hagstrom, E., Brene, S., Mourier, A., Coppotelli, G., Freyer, C., Lagouge, M., Hoffer, B. J., Olson, L., & Larsson, N. (2013). Germline mitochondrial DNA mutations aggravate ageing and can impair brain development. Nature, 501(7467), 412-5. doi:10.1038/nature12474. [PubMan] : Baggio, F., Bratic, A., Mourier, A., Kukat, C., Habermann, B., Partridge, L., & Larsson, N. (2013). Role of the mitochondrial protein LRPPRC2 in Drosophila melanogaster. MITOCHONDRION, 13(6), 909-909. doi:10.1016/j.mito.2013.07.032. [PubMan] : Wredenberg, A., Lagouge, M., Bratic, A., Metodiev, M. D., Spahr, H., Mourier, A., Freyer, C., Ruzzenente, B., Tain, L. S., Grönke, S., Baggio, F., Kukat, C., Kremmer, E., Wibom, R., Polosa, P. L., Habermann, B., Partridge, L., Park, C. B., & Larsson, N. (2013). MTERF3 regulates mitochondrial ribosome biogenesis in invertebrates and mammals. PLoS Genet, 9(1), e1003178. doi:10.1371/journal.pgen.1003178. [PubMan]