Researcher Portfolio
Alnouri, Mohamad Wessam
Pharmacology, Max Planck Institute for Heart and Lung Research, Max Planck Society
Researcher Profile
Position: Pharmacology, Max Planck Institute for Heart and Lung Research, Max Planck Society
Researcher ID: https://pure.mpg.de/cone/persons/resource/persons261924
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Publications
: Jin, Y.-J., Liang, G., Li, R., Wang, S., Alnouri, M. W., Bentsen, M., Kuenne, C., Guenther, S., Yan, Y., Li, Y., Wettschureck, N., & Offermanns, S. (2025). Phosphorylation of endothelial histone H3.3 serine 31 by PKN1 links flow-induced signaling to proatherogenic gene expression. NATURE CARDIOVASCULAR RESEARCH, 4(2). doi:10.1038/s44161-024-00593-y. [PubMan] : Hernandez-Olmos, V., Heering, J., Ildefeld, N., Ehrler, J. H. M., Kaps, A., Rajkumar, R., Marinescu, B., Kaiser, A., Macinkovic, I., Elewa, M. A. F., Alnouri, M. W., Elson, L., Schubert-Zsilavecz, M., Kallenborn-Gerhardt, W., Schmidtko, A., Mueller, S., Offermanns, S., Steinhilber, D., Weigert, A., & Proschak, E. (2025). Identification of a Chemical Probe for BLT2 Activation by Scaffold Hopping. JOURNAL OF MEDICINAL CHEMISTRY, 68(2), 1195-1221. doi:10.1021/acs.jmedchem.4c01617. [PubMan] : Alnouri, M. W., Roquid, K. A., Bonnavion, R., Cho, H., Heering, J., Kwon, J., Jaeger, Y., Wang, S., Guenther, S., Wettschureck, N., Geisslingerb, G., Gurke, R., Mueller, C. E., Proschak, E., & Offermanns, S. (2024). SPMs exert anti- inflammatory and pro- resolving effects through positive allosteric modulation of the prostaglandin EP4 receptor. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 121(41): e2407130121. doi:10.1073/pnas.2407130121. [PubMan] : Hernandez-Olmos, V., Heering, J., Marinescu, B., Schermeng, T., Ivanov, V. V., Moroz, Y. S., Nevermann, S., Mathes, M., Ehrler, J. H. M., Alnouri, M. W., Wolf, M., Haydo, A. S., Schmachtel, T., Zaliani, A., Ho''fner, G., Kaiser, A., Schubert-Zsilavecz, M., Beck-Sickinger, A. G., Offermanns, S., Gribbon, P., Rieger, M. A., Merk, D., Sisignano, M., Steinhilber, D., & Proschak, E. (2024). Development of a Potent and Selective G2A (GPR132) Agonist. JOURNAL OF MEDICINAL CHEMISTRY. doi:10.1021/acs.jmedchem.3c02164. [PubMan] : Wang, T., Shao, J., Shamit, K., Alnouri, M. W., Carvalho, J., Guenther, S., Krasel, C., Murphy, K. T., Buenemann, M., Offermanns, S., & Wettschureck, N. (2024). Orphan GPCR GPRC5C Facilitates Angiotensin II-Induced Smooth Muscle Contraction. CIRCULATION RESEARCH, 134(10), 1259-1275. doi:10.1161/CIRCRESAHA.123.323752. [PubMan] : Marx, D., Alnouri, M. W., Clemens, S., Gedschold, R., Riedel, Y., Al Hamwi, G., Pillaiyar, T., Hockemeyer, J., Namasivayam, V., & Mueller, C. E. (2023). Discovery of Potent Agonists for the Predominant Variant of the Orphan MAS-Related G Protein-Coupled Receptor X4 (MRGPRX4). JOURNAL OF MEDICINAL CHEMISTRY, 66(23), 15674-15698. doi:10.1021/acs.jmedchem.3c01013. [PubMan] : Wedel, S., Hahnefeld, L., Alnouri, M. W., Offermanns, S., Hausch, F., Geisslinger, G., & Sisignano, M. (2022). The FKBP51 Inhibitor SAFit2 Restores the Pain-Relieving C16 Dihydroceramide after Nerve Injury. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(22): 14274. doi:10.3390/ijms232214274. [PubMan] : Schebb, N. H., Kuehn, H., Kahnt, A. S., Rund, K. M., O'Donnell, V. B., Flamand, N., Peters-Golden, M., Jakobsson, P.-J., Weylandt, K. H., Rohwer, N., Murphy, R. C., Geisslinger, G., FitzGerald, G. A., Hanson, J., Dahlgren, C., Alnouri, M. W., Offermanns, S., & Steinhilber, D. (2022). Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators-What is the Evidence so far? FRONTIERS IN PHARMACOLOGY, 13: 838782. doi:10.3389/fphar.2022.838782. [PubMan] : Le Mercier, A., Bonnavion, R., Yu, W., Alnouri, M. W., Ramas, S., Zhang, Y., Jaeger, Y., Roquid, K. A., Jeong, H.-W., Sivaraj, K. K., Cho, H., Chen, X., Strilic, B., Sijmonsma, T., Adams, R., Schroeder, T., Rieger, M. A., & Offemanns, S. (2021). GPR182 is an endothelium-specific atypical chemokine receptor that maintains hematopoietic stem cell homeostasis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 118(17): e2021596118. doi:10.1073/pnas.2021596118. [PubMan]