Researcher Portfolio
Hernandez Alvarez, Birte
Conservation of Protein Structure and Function Group, Department Protein Evolution, Max Planck Institute for Biology Tübingen, Max Planck Society, Conservation of Protein Structure and Function Group, Department Protein Evolution, Max Planck Institute for Developmental Biology, Max Planck Society, Department Cell Biology, Max Planck Institute for Developmental Biology, Max Planck Society, Department Protein Evolution, Max Planck Institute for Biology Tübingen, Max Planck Society, Department Protein Evolution, Max Planck Institute for Developmental Biology, Max Planck Society
Researcher Profile
Position: Department Protein Evolution, Max Planck Institute for Biology Tübingen, Max Planck Society
Position: Department Protein Evolution, Max Planck Institute for Developmental Biology, Max Planck Society
Position: Conservation of Protein Structure and Function Group, Department Protein Evolution, Max Planck Institute for Biology Tübingen, Max Planck Society
Position: Conservation of Protein Structure and Function Group, Department Protein Evolution, Max Planck Institute for Developmental Biology, Max Planck Society
Position: Department Cell Biology, Max Planck Institute for Developmental Biology, Max Planck Society
Additional IDs: MPIB: birteh
ORCID: https://orcid.org/0000-0003-0635-8698
ORCID: https://orcid.org/0000-0003-0635-8698
Researcher ID: https://pure.mpg.de/cone/persons/resource/persons271242
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Publications
(1 - 25 of 64)
: Borbaran Bravo, N., Deordieva, E., Doll, L., ElGamacy, M., Dannenmann, B., Azevedo, J., Iannuzzo, A., Delafontaine, S., Lehnerz, M., Kolodziej, M., Hernandez-Alvarez, B., Hellmuth, A.-S., Findik, B., Zakharova, V., Bräuning, S., Kandabarau, S., Lengerke, C., Feil, R., Meytz, I., Delon, J., Templin, M., Sturm, M., Rieß, O., Zeidler, C., Welte, K., Shcherbina, A., Klimiankou, M., & Skokowa, J. (2024). A New Severe Congenital Neutropenia Syndrome Associated with Autosomal Recessive COPZ1 Mutations. Blood, Epub ahead. doi:10.1182/blood.2023022576. [PubMan] : Ullrich, T., Hernandez-Alvarez, B., Pollmann, C., Ritter, M., Haaf, J., Aghaallaei, N., Piehler, J., Tesakov, I., El-Riz, M., Maksymenko, K., Hatskovska, V., Kandabarua, S., Klimiankou, M., Lengerke, C., Welte, K., Lupas, A., Skokowa, J., & ElGamacy, M. (2024). Modulating G-CSFR Signaling Using De Novo Designed Cytokines. Poster presented at 66th ASH Annual Meeting, San Diego, CA, USA. [PubMan] : Borbaran Bravo, N., Deordieva, E., Doll, L., ElGamacy, M., Dannenmann, B., Azevedo, J., Iannuzzo, A., Delafontaine, S., Lehners, M., Kolodziej, M., Hernandez Alvarez, B., Hellmuth, A., Ritter, M., Findik, B., Zakharova, V., Bräuning, S., Kandabarau, S., Lengerke, C., Feil, R., Meyts, I., Delon, J., Templin, M., Sturm, M., Rieß, O., Zeidler, C., Welte, K., Shcherbina, A., Klimiankou, M., & Skokowa, J. (2024). Autosomal Recessive COPZ1 Mutations Cause Isolated Severe Neutropenia or Complex Syndrome with Severe Neutropenia. Poster presented at 66th ASH Annual Meeting, San Diego, CA, USA. [PubMan] : Schwab, S., Hu, Y., van Erp, B., Kajili, M., Hartmann, M., Hernandez-Alvarez, B., Alva, V., Boyle, A., & Dame, R. (2024). Novel histones and histone variant families in prokaryotes. Nature Communications, 15(1): 7950. doi:10.1038/s41467-024-52337-y. [PubMan] : Hatskovska, V., Skokowa, J., Hernandez-Alvarez, B., Piehler, J., Lupas, A., & ElGamacy, M. (2024). De novo Design and Characterization of Bispecific Cytokines with Novel Function. Poster presented at 23rd European Conference on Computational Biology (ECCB 2024), Turku, Finland. [PubMan] : Hu, Y., Schwab, S., Deiss, S., Escudeiro, P., van Heesch, T., Joiner, J., Vreede, J., Hartmann, M., Lupas, A., Hernandez Alvarez, B., Alva, V., & Dame, R. (2024). Bacterial histone HBb from Bdellovibrio bacteriovorus compacts DNA by bending. Nucleic Acids Research, 52(14): gkae485, pp. 8193-8204. doi:10.1093/nar/gkae485. [PubMan] : Hu, Y., Schwab, S., Escudeiro, P., van Heesch, T., Vreede, J., Hartmann, M., Lupas, A., Dame, R., Alva, V., & Hernandez Alvarez, B. (2024). Bacterial histone HBb from Bdellovibrio bacteriovorus compacts DNA by bending. In Molecular Origins of LIFE (pp. 59). [PubMan] : Ullrich, T., Pollmann, C., Ritter, M., Haaf, J., Aghaallae, N., Tesakov, I., El-Riz, M., Maksymenko, K., Hatskovska, V., Kandabarau, S., Klimiankou, M., Lengerke, C., Welte, K., Hernandez-Alvarez, B., Müller, P., Lupas, A., Piehler, J., Skokowa, J., & ElGamacy, M. (submitted). Tuning of granulopoietic signaling by de novo designed agonists. [PubMan] : Ullrich, T., Pollmann, C., Ritter, M., Haaf, J., Aghaallae, N., Tesakov, I., El-Riz, M., Maksymenko, K., Hatskovska, V., Kandabarau, S., Klimiankou, M., Lengerke, C., Welte, K., Hernandez-Alvarez, B., Müller, P., Lupas, A., Piehler, J., Skokowa, J., & ElGamacy, M. (submitted). Tuning of granulopoietic signaling by de novo designed agonists. [PubMan] : Maksymenko, K., Maurer, A., Aghaallaei, N., Barry, C., Borbarán-Bravo, N., Ullrich, T., Dijkstra, T., Hernandez-Alvarez, B., Müller, P., Lupas, A., Skokowa, J., & ElGamacy, M. (2023). The design of functional proteins using tensorized energy calculations. Cell Reports Methods, 3(8): 100560. doi:10.1016/j.crmeth.2023.100560. [PubMan] : Maksymenko, K., Maurer, A., Aghaallaei, N., Barry, C., Borbarán-Bravo, N., Ullrich, T., Dijkstra, T., Hernandez-Alvarez, B., Müller, P., Lupas, A., Skokowa, J., & ElGamacy, M. (2023). The design of functional proteins using tensorized energy calculations. Cell Reports Methods, 3(8): 100560. doi:10.1016/j.crmeth.2023.100560. [PubMan] : Hu, Y., Deiss, S., Joiner, J., Hartmann, M., Lupas, A., Hernandez Alvarez, B., & Alva, V. (submitted). Atomic resolution structure of a DNA-binding histone protein from the bacterium Bdellovibrio bacteriovorus. [PubMan] : Hernandez Alvarez, B. (2022). Towards a coiled coil with a polar core. In 8th Alpbach Workshop: Coiled Coil, Fibrous and Repeat Proteins (pp. 27). [PubMan] : Maksymenko, K., Hernandez Alvarez, B., Ullrich, T., Skokowa, J., Lupas, A., & ElGamacy, M. (2022). Damietta: A Tensorised Protein Design Engine, and Its Application in Therapeutic Protein Design. In 8th Alpbach Workshop: Coiled Coil, Fibrous and Repeat Proteins (pp. 22). [PubMan] : Lupas, A., Dunin-Horkawicz, S., Martinez-Goikoetxea, M., Hartmann, M., & Hernandez Alvarez, B. (2022). The structural diversity of natural coiled coils. In 8th Alpbach Workshop: Coiled Coil, Fibrous and Repeat Proteins (pp. 39). [PubMan] : ElGamacy, M., Ullrich, T., Maksymenko, K., Lupas, A., Hernandez, B., & Skokowa, J. (2022). De novo design of cytokines, antikines, and novokines. Klinische Pädiatrie, 234(03): 0051, 185. [PubMan] : Skokowa, J., Hernandez Alvarez, B., Coles, M., Ritter, M., Nasri, M., Haaf, J., Aghaallaei, N., Xu, Y., Mir, P., Krahl, A.-C., Rogers, K., Maksymenko, K., Bajoghli, B., Welte, K., Lupas, A., Müller, P., & ElGamacy, M. (2022). A topological refactoring design strategy yields highly stable granulopoietic proteins. Nature Communications, 13(1): 2948. doi:10.1038/s41467-022-30157-2. [PubMan] : Skokowa, J., Hernandez Alvarez, B., Coles, M., Ritter, M., Nasri, M., Haaf, J., Aghaallaei, N., Xu, Y., Mir, P., Krahl, A.-C., Rogers, K., Maksymenko, K., Bajoghli, B., Welte, K., Lupas, A., Müller, P., & ElGamacy, M. (2022). A topological refactoring design strategy yields highly stable granulopoietic proteins. Nature Communications, 13(1): 2948. doi:10.1038/s41467-022-30157-2. [PubMan] : Maksymenko, K., Hernandez Alvarez, B., Ullrich, T., Müller, P., Skokowa, J., Lupas, A., & ElGamacy, M. (2022). Damietta: A Tensorised Protein Design Engine, and Its Application in Therapeutic Protein Design. In Advances in Protein Folding, Evolution and Design (APFED 2022) (pp. 67). [PubMan] : Maksymenko, K., Hernandez Alvarez, B., Ullrich, T., Müller, P., Skokowa, J., Lupas, A., & ElGamacy, M. (2022). Damietta: A Tensorised Protein Design Engine, and Its Application in Therapeutic Protein Design. In Advances in Protein Folding, Evolution and Design (APFED 2022) (pp. 67). [PubMan] : Maiwald, S., Heim, C., Hernandez Alvarez, B., & Hartmann, M. (2021). Correction to "Sweet and Blind Spots in E3 Ligase Ligand Space Revealed by a Thermophoresis-Based Assay". ACS Medicinal Chemistry Letters, 13(1), 148-149. doi:10.1021/acsmedchemlett.1c00693. [PubMan] : ElGamacy, M., Hernandez Alvarez, B., Skokowa, J., & Lupas, A. (2021). Damietta: A Tensorised Protein Design Engine, and Its Application in Therapeutic Protein Engineering. Protein Science, 30(Supplement 1): 142, 62. [PubMan] : ElGamacy, M., & Hernandez Alvarez, B. (2021). Expanding the versatility of natural and de novo designed coiled coils and helical bundles. Current Opinion in Structural Biology, 68, 224-234. doi:10.1016/j.sbi.2021.03.011. [PubMan] : ElGamacy, M., & Hernandez Alvarez, B. (2021). Expanding the versatility of natural and de novo designed coiled coils and helical bundles. Current Opinion in Structural Biology, 68, 224-234. doi:10.1016/j.sbi.2021.03.011. [PubMan] : ElGamacy, M., Hernandez-Alvarez, B., & Skokowa, J.(2020). Novel g-csf mimics and their applications. [PubMan]