Researcher Portfolio
Dr. Stricker, Sigmar
Research Group Development & Disease (Head: Stefan Mundlos), Max Planck Institute for Molecular Genetics, Max Planck Society
Researcher Profile
Position: Research Group Development & Disease (Head: Stefan Mundlos), Max Planck Institute for Molecular Genetics, Max Planck Society
Researcher ID: https://pure.mpg.de/cone/persons/resource/persons50578
Publications
(1 - 25 of 58)
: Orgeur, M., Martens, M., Leonte, G., Nassari, S., Bonnin, M.-A., Börno, S. T., Timmermann, B., Hecht, J., Duprez, D., & Stricker, S. (2018). Genome-wide strategies identify downstream target genes of connective tissue-associated transcription factors. Development, 145(7): dev161208. doi:10.1242/dev.161208. [PubMan] : Orgeur, M., Martens, M., Börno, S. T., Timmermann, B., Duprez, D., & Stricker, S. (2018). A dual transcript-discovery approach to improve the delimitation of gene features from RNA-seq data in the chicken model. Biology Open, 7(1): bio.028498. doi:10.1242/bio.028498. [PubMan] : Vallecillo-García, P., Orgeur, M., vom Hofe-Schneider, S., Stumm, J., Kappert, V., Ibrahim, D., Börno, S. T., Hayashi, S., Relaix, F., Hildebrandt, K., Sengle, G., Koch, M., Timmermann, B., Marazzi, G., Sassoon, D. A., Duprez, D., & Stricker, S. (2017). Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development. Nature Communications, 8(1): 1218. doi:10.1038/s41467-017-01120-3. [PubMan] : Knierim, E., Hirata, H., Wolf, N. I., Morales-Gonzalez, S., Schottmann, G., Tanaka, Y., Rudnik-Schöneborn, S., Orgeur, M., Zerres, K., Vogt, S., van Riesen, A., Gill, E., Seifert, F., Zwirner, A., Kirschner, J., Goebel, H. H., Hübner, C., Stricker, S., Meierhofer, D., Stenzel, W., & Schuelke, M. (2016). Mutations in Subunits of the Activating Signal Cointegrator 1 Complex Are Associated with Prenatal Spinal Muscular Atrophy and Congenital Bone Fractures. The American Journal of Human Genetics, 98, 1-17. doi:10.1016/j.ajhg.2016.01.006. [PubMan] : Maass, P. G., Aydin, A., Luft, F. C., Schachterle, C., Weise, A., Stricker, S., Lindschau, C., Vaegler, M., Qadri, F., Toka, H. R., Schulz, H., Krawitz, P. M., Parkhomchuk, D., Hecht, J., Hollfinger, I., Wefeld-Neuenfeld, Y., Bartels-Klein, E., Muhl, A., Kann, M., Schuster, H., Chitayat, D., Bialer, M. G., Wienker, T. F., Ott, J., Rittscher, K., Liehr, T., Jordan, J., Plessis, G., Tank, J., Mai, K., Naraghi, R., Hodge, R., Hopp, M., Hattenbach, L. O., Busjahn, A., Rauch, A., Vandeput, F., Gong, M., Ruschendorf, F., Hübner, N., Haller, H., Mundlos, S., Bilginturan, N., Movsesian, M. A., Klussmann, E., Toka, O., & Bahring, S. (2015). PDE3A mutations cause autosomal dominant hypertension with brachydactyly. Nature Genetics, 47(6), 647-653. doi:10.1038/ng.3302. [PubMan] : Ott, C. E., Hein, H., Lohan, S., Hoogeboom, J., Foulds, N., Grunhagen, J., Stricker, S., Villavicencio-Lorini, P., Klopocki, E., & Mundlos, S. (2012). Microduplications upstream of MSX2 are associated with a phenocopy of cleidocranial dysplasia. Journal of Medical Genetics (London), 49(7), 437-441. doi:10.1136/jmedgenet-2012-100825. [PubMan] : Klopocki, E., Lohan, S., Doelken, S. C., Stricker, S., Ockeloen, C. W., Soares Thiele de Aguiar, R., Lezirovitz, K., Netto, M., Jamsheer, A., Shah, H., Kurth, I., Habenicht, R., Warman, M., Devriendt, K., Kordass, U., Hempel, M., Rajab, A., Makitie, O., Naveed, M., Radhakrishna, U., Antonarakis, S. E., Horn, D., & Mundlos, S. (2012). Duplications of BHLHA9 are associated with ectrodactyly and tibia hemimelia inherited in non-Mendelian fashion. Journal of Medical Genetics (London), 49(2), 119-125. doi:10.1136/jmedgenet-2011-100409. [PubMan] : Stricker, S., Mathia, S., Haupt, J., Seemann, P., Meier, J., & Mundlos, S. (2012). Odd-skipped related genes regulate differentiation of embryonic limb mesenchyme and bone marrow mesenchymal stromal cells. Stem Cells and Development, 21(4), 623-633. doi:10.1089/scd.2011.0154. [PubMan] : Klopocki, E., Lohan, S., Doelken, S. C., Stricker, S., Ockeloen, C. W., Soares Thiele de Aguiar, R., Lezirovitz, K., Mingroni Netto, R. C., Jamsheer, A., Shah, H., Kurth, I., Habenicht, R., Warman, M., Devriendt, K., Kordass, U., Hempel, M., Rajab, A., Makitie, O., Naveed, M., Radhakrishna, U., Antonarakis, S. E., Horn, D., & Mundlos, S. (2012). Duplications of BHLHA9 are associated with ectrodactyly and tibia hemimelia inherited in non-Mendelian fashion. J Med Genet, 49(2), 119-125. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/22147889 http://jmg.bmj.com/content/49/2/119.full.pdf. [PubMan] : Klopocki, E., Lohan, S., Brancati, F., Koll, R., Brehm, A., Seemann, P., Dathe, K., Stricker, S., Hecht, J., Bosse, K., Betz, R. C., Garaci, F. G., Dallapiccola, B., Jain, M., Muenke, M., Ng, V. C., Chan, W., Chan, D., & Mundlos, S. (2011). Copy-number variations involving the IHH locus are associated with syndactyly and craniosynostosis. American Journal of Human Genetics, 88(1), 70-75. doi:i:10.1016/j.ajhg.2010.11.006. [PubMan] : Stricker, S., Mathia, S., Haupt, J., Seemann, P., Meier, J., & Mundlos, S. (2011). Odd-Skipped Related Genes Regulate Differentiation of Embryonic Limb Mesenchyme and Bone Marrow Mesenchymal Stromal Cells. Stem Cells Dev. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/21671783 http://online.liebertpub.com/doi/pdfplus/10.1089/scd.2011.0154. [PubMan] : Stricker, S., & Mundlos, S. (2011). Mechanisms of digit formation: Human malformation syndromes tell the story. Dev Dyn, 240(5), 990-1004. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/21337664 http://onlinelibrary.wiley.com/store/10.1002/dvdy.22565/asset/22565_ftp.pdf?v=1&t=gyzw8k94&s=70c87ec284feabc059aa18c47a8f946bd2472c6b. [PubMan] : Kossler, N., Stricker, S., Rodelsperger, C., Robinson, P. N., Kim, J., Dietrich, C., Osswald, M., Kuhnisch, J., Stevenson, D. A., Braun, T., Mundlos, S., & Kolanczyk, M. (2011). Neurofibromin (Nf1) is required for skeletal muscle development. Hum Mol Genet, 20(14), 2697-709. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/21478499 http://hmg.oxfordjournals.org/content/20/14/2697.full.pdf. [PubMan] : Baasanjav, S., Al-Gazali, L., Hashiguchi, T., Mizumoto, S., Fischer, B., Horn, D., Seelow, D., Ali, B. R., Aziz, S. A., Langer, R., Saleh, A. A., Becker, C., Nurnberg, G., Cantagrel, V., Gleeson, J. G., Gomez, D., Michel, J. B., Stricker, S., Lindner, T. H., Nurnberg, P., Sugahara, K., Mundlos, S., & Hoffmann, K. (2011). Faulty initiation of proteoglycan synthesis causes cardiac and joint defects. Am J Hum Genet, 89(1), 15-27. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/21763480 http://pdn.sciencedirect.com/science?_ob=MiamiImageURL&_cid=276895&_user=28761&_pii=S000292971100214X&_check=y&_origin=article&_zone=toolbar&_coverDate=15-Jul-2011&view=c&originContentFamily=serial&wchp=dGLzVlB-zSkzS&md5=649207de536a6fe4c92490e7b79131b7/1-s2.0-S000292971100214X-main.pdf. [PubMan] : Klopocki, E., Lohan, S., Brancati, F., Koll, R., Brehm, A., Seemann, P., Dathe, K., Stricker, S., Hecht, J., Bosse, K., Betz, R. C., Garaci, F. G., Dallapiccola, B., Jain, M., Muenke, M., Ng, V. C., Chan, W., Chan, D., & Mundlos, S. (2011). Copy-number variations involving the IHH locus are associated with syndactyly and craniosynostosis. Am J Hum Genet, 88(1), 70-5. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/21167467 http://pdn.sciencedirect.com/science?_ob=MiamiImageURL&_cid=276895&_user=28761&_pii=S0002929710005938&_check=y&_origin=article&_zone=toolbar&_coverDate=07-Jan-2011&view=c&originContentFamily=serial&wchp=dGLzVlV-zSkzS&md5=1e0d2c33fcb13c2c5a4fff5884303f09/1-s2.0-S0002929710005938-main.pdf. [PubMan] : Stricker, S., & Mundlos, S. (2011). FGF and ROR2 receptor tyrosine kinase signaling in human skeletal development. Curr Top Dev Biol, 97, 179-206. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/22074606. [PubMan] : Stricker, S. (2010). Molekulargenetik und funktionelle Analyse embryonaler Extremitätenfehlbildungen. Habilitation Thesis, Charité- Univeristätsmedizin Berlin, Berlin. [PubMan] : Brancati, F., Fortugno, P., Bottillo, I., Lopez, M., Josselin, E., Boudghene-Stambouli, O., Agolini, E., Bernardini, L., Bellacchio, E., Iannicelli, M., Rossi, A., Dib-Lachachi, A., Stuppia, L., Palka, G., Mundlos, S., Stricker, S., Kornak, U., Zambruno, G., & Dallapiccola, B. (2010). Mutations in PVRL4, encoding cell adhesion molecule nectin-4, cause ectodermal dysplasia-syndactyly syndrome. American Journal of Human Genetics, 87(2), 265-273. doi:10.1016/j.ajhg.2010.07.003. [PubMan] : Witte, F., Chan, D., Economides, A. N., Mundlos, S., & Stricker, S. (2010). Receptor tyrosine kinase-like orphan receptor 2 (ROR2) and Indian hedgehog regulate digit outgrowth mediated by the phalanx-forming region. Proceedings of the National Academy of Sciences U S A, 107(32), 14211-14216. doi:10.1073/pnas.1009314107. [PubMan] : Clayton, P., Fischer, B., Mann, A., Mansour, S., Rossier, E., Veen, M., Lang, C., Baasanjav, S., Kieslich, M., Brossuleit, K., Gravemann, S., Schnipper, N., Karbasyian, M., Demuth, I., Zwerger, M., Vaya, A., Utermann, G., Mundlos, S., Stricker, S., Sperling, K., & Hoffmann, K. (2010). Mutations causing Greenberg dysplasia but not Pelger anomaly uncouple enzymatic from structural functions of a nuclear membrane protein. Nucleus, 1(4), 354-366. doi:10.4161/nucl.1.4.12435. [PubMan] : Witte, F., Bernatik, O., Kirchner, K., Masek, J., Mahl, A., Krejci, P., Mundlos, S., Schambony, A., Bryja, V., & Stricker, S. (2010). Negative regulation of Wnt signaling mediated by CK1-phosphorylated Dishevelled via Ror2. The FASEB Journal, 24(7), 2417-2426. doi:10.1096/fj.09-150615. [PubMan] : Jensen, L. R., Bartenschlager, H., Rujirabanjerd, S., Tzschach, A., Nümann, A., Janecke, A. R., Spörle, R., Stricker, S., Raynaud, M., Nelson, J., Hackett, A., Fryns, J.-P., Chelly, J., de Brouwer, A. P. M., Hamel, B., Gecz, J., Ropers, H.-H., & Kuss, A. W. (2010). A distinctive gene expression fingerprint in mentally retarded male patients reflects disease-causing defects in the histone demethylase KDM5C. Pathogenetics, 3, 2-2. doi:10.1186/1755-8417-3-2. [PubMan] : Jensen, L. R., Bartenschlager, H., Rujirabanjerd, S., Tzschach, A., Nümann, A., Janecke, A. R., Spörle, R., Stricker, S., Raynaud, M., Nelson, J., Hackett, A., Fryns, J.-P., Chelly, J., de Brouwer, A. P. M., Hamel, B., Gecz, J., Ropers, H.-H., & Kuss, A. W. (2010). A distinctive gene expression fingerprint in mentally retarded male patients reflects disease-causing defects in the histone demethylose KDM5C. Pathogenetics, 2(3), 2-2. doi:10.1186/1755-8417-3-2. [PubMan] : Liska, F., Snajdr, P., Stricker, S., Gosele, C., Krenova, D., Mundlos, S., & Hubner, N. (2010). Impairment of Sox9 expression in limb buds of rats homozygous for hypodactyly mutation. Folia Biologica, 56(2), 58-65. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/20492757. [PubMan] : van Wijk, N. V., Witte, F., Feike, A. C., Schambony, A., Birchmeier, W., Mundlos, S., & Stricker, S. (2009). The LIM domain protein Wtip interacts with the receptor tyrosine kinase Ror2 and inhibits canonical Wnt signalling. Biochemical and Biophysical Research Communications, 390(2), 211-216. Retrieved from http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6WBK-4X9TTRS-3-7&_cdi=6713&_user=127795&_pii=S0006291X09018956&_orig=browse&_coverDate=12%2F11%2F2009&_sk=996099997&view=c&wchp=dGLzVzz-zSkWb&md5=c9f5ca81e4f3eb0d7f3d49493d36036c&ie=/sdarticle.pdf. [PubMan]