Researcher Portfolio

Höber, Barbara

Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society

Researcher Profile

Position: Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society

Researcher ID: https://pure.mpg.de/cone/persons/resource/persons72752

External references

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Publications

: Kulik, M., Bothe, M., Kibar, G., Fuchs, A., Schöne, S., Prekovic, S., Mayayo Peralta, I., Chung, H.-R., Zwart, W., Helsen, C., Claessens, F., & Meijsing, S. (2021). Androgen and glucocorticoid receptor direct distinct transcriptional programs by receptor-specific and shared DNA binding sites. Nucleic Acids Research (London), 49(7), 3856-3875. doi:10.1093/nar/gkab185. [PubMan] : Ramisch, A., Heinrich, V., Glaser, L. V., Fuchs, A., Yang, X., Benner, P., Schöpflin, R., Li, N., Kinkley, S., Römer-Hillmann, A., Longinotto, J., Heyne, S., Czepukojc, B., Kessler, S. M., Kiemer, A. K., Cadenas, C., Arrigoni, L., Gasparoni, N., Manke, T., Pap, T., Pospisilik, A., Hengstler, J., Walter, J., Meijsing, S., Chung, H.-R., & Vingron, M. (2019). CRUP: a comprehensive framework to predict condition-specific regulatory units. Genome Biology: Biology for the Post-Genomic Era, 20(1): 227. doi:10.1186/s13059-019-1860-7. [PubMan] : Li, H., Kaiser, T. K., Borschiwer, M., Bohnenberger, H., Reichardt, S. D., Luhder, F., Walter, L., Dressel, R., Meijsing, S., & Reichardt, H. M. (2019). Glucocorticoid resistance of allogeneic T cells alters the gene expression profile in the inflamed small intestine of mice suffering from acute graft-versus-host disease. Journal of Steroid Biochemistry and Molecular Biology, 195: 105485. doi:10.1016/j.jsbmb.2019.105485. [PubMan] : Malik, V., Glaser, L. V., Zimmer, D., Velychko, S., Weng, M., Holzner, M., Arend, M., Chen, Y., Srivastava, Y., Veerapandian, V., Shah, Z., Esteban, M. A., Wang, H., Chen, J., Scholer, H. R., Hutchins, A. P., Meijsing, S. H., Pott, S., & Jauch, R. (2019). Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2. Nature Communications, 10(1): 3477. doi:10.1038/s41467-019-11054-7. [PubMan] : Thormann, V., Glaser, L. V., Rothkegel, M. C., Borschiwer, M., Bothe, M., Fuchs, A., & Meijsing, S. H. (2019). Expanding the repertoire of glucocorticoid receptor target genes by engineering genomic response elements. Life Science Alliance, 2(2): e201800283. doi:10.26508/lsa.201800283. [PubMan] : Schöne, S., Bothe, A. M., Einfeldt, E., Borschiwer, M., Benner, P. F., Vingron, M., Thomas-Chollier, M., & Meijsing, S. H. (2018). Synthetic STARR-seq reveals how DNA shape and sequence modulate transcriptional output and noise. PLoS Genetics, 14(11): e1007793. doi:10.1371/journal.pgen.1007793. [PubMan] : Tolkachov, A., Fischer, C., Ambrosi, T. H., Bothe, A. M., Han, C.-T., Muenzner, M., Mathia, S., Salminen, M., Seifert, G., Thiele, M., Duda, G. N., Meijsing, S., Sauer, S., Schulz, T. J., & Schupp, M. (2018). Loss of the hematopoietic stem cell factor GATA2 in the osteogenic lineage impairs trabecularization and mechanical strength of bone. Molecular and Cellular Biology (Washington, DC), 38(12): e00599-17. doi:10.1128/MCB.00599-17. [PubMan] : Thormann, V., Rothkegel, M. C., Schöpflin, R., Glaser, L. V., Djuric, P., Li, N., Chung, H.-R., Schwahn, K., Vingron, M., & Meijsing, S. (2018). Genomic dissection of enhancers uncovers principles of combinatorial regulation and dynamic wiring of enhancer-promoter contacts. Nucleic Acids Research (London), 46(6), 2868-2882. doi:10.1093/nar/gky051. [PubMan] : Klaßen, C., Karabinskaya, A., Dejager, L., Vettorazzi, S., Van Moorleghem, J., Lühder, F., Meijsing, S. H., Tuckermann, J. P., Bohnenberger, H., Libert, C., & Reichardt, H. M. (2017). Airway Epithelial Cells Are Crucial Targets of Glucocorticoids in a Mouse Model of Allergic Asthma. Journal of Immunology, 199(1), 48-61. doi:10.4049/jimmunol.1601691. [PubMan] : Love, M. I., Huska, M., Jurk, M., Schöpflin, R., Starick, S. R., Schwahn, K., Cooper, S. B., Yamamoto, K. R., Thomas-Chollier, M., Vingron, M., & Meijsing, S. H. (2017). Role of the chromatin landscape and sequence in determining cell type-specific genomic glucocorticoid receptor binding and gene regulation. Nucleic Acids Research (London), 45(4), 1805-1819. doi:10.1093/nar/gkw1163. [PubMan] : Birth, P., Schöne, S., Stelzl, U., & Meijsing, S. H. (2017). Identification and characterization of BATF3 as a context-specific coactivator of the glucocorticoid receptor. PLoS One, 12(7): e0181219. doi:10.1371/journal.pone.0181219. [PubMan] : Batalha, V., Ferreira, D. G., Coelho, J. E., Valadas, J. S., Gomes, R., Temido-Ferreira, M., Shmidt, T., Baqi, Y., Buée, L., Müller, C. E., Hamdane, M., Outeiro, T. F., Bader, M., Meijsing, S., Sadri-Vakili, G., Blum, D., & Lopes, L. V. (2016). The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function. Scientific Reports, 6: 31493. doi:10.1038/srep31493. [PubMan] : Telorac, J., Prykhozhij, S., Schöne, S., Meierhofer, D., Sauer, S., Thomas-Chollier, M., & Meijsing, S. H. (2016). Identification and characterization of DNA sequences that prevent glucocorticoid receptor binding to nearby response elements. Nucleic Acids Research (London), 44(13), 6142-6156. doi:10.1093/nar/gkw203. [PubMan] : Schöne, S., Jurk, M., Helabad, M. B., Dror, I., Lebars, I., Kieffer, B., Imhof, P., Rohs, R., Vingron, M., Thomas-Chollier, M., & Meijsing, S. (2016). Corrigendum: Sequences flanking the core-binding site modulate glucocorticoid receptor structure and activity. Nature Communications, 7: 13784. doi:10.1038/ncomms13784. [PubMan] : Schöne, S., Jurk, M., Helabad, M. B., Dror, I., Lebars, I., Kieffer, B., Imhof, P., Rohs, R., Vingron, M., Thomas-Chollier, M., & Meijsing, S. (2016). Sequences flanking the core-binding site modulate glucocorticoid receptor structure and activity. Nature Communications, 7: 12621. doi:10.1038/ncomms12621. [PubMan] : Starick, S. R., Ibn-Salem, J., Jurk, M., Hernandez, C., Love, M. I., Chung, H.-R., Vingron, M., Thomas-Chollier, M., & Meijsing, S. H. (2015). ChIP-exo signal associated with DNA-binding motifs provides insight into the genomic binding of the glucocorticoid receptor and cooperating transcription factors. Genome Res, 25(6), 825-835. doi:10.1101/gr.185157.114. [PubMan] : Meijsing, S. H. (2015). Mechanisms of Glucocorticoid-Regulated Gene Transcription. In J.-C. Wang, & C. Harris (Eds.), Glucocorticoid Signaling: From Molecules to Mice to Man. [PubMan] : Thomas-Chollier, M., Watson, L. C., Cooper, S. B., Pufall, M. A., Liu, J. S., Borzym, K., Vingron, M., Yamamoto, K. R., & Meijsing, S. H. (2013). A naturally occuring insertion of a single amino acid rewires transcriptional regulation by glucocorticoid receptor isoforms. Proceedings of the National Academy of Sciences of the United States of America, 110(44), 17826-17831. doi:10.1073/pnas.1316235110. [PubMan] : Prykhozhij, S., Marsico, A., & Meijsing, S. (2013). Zebrafish Expression Ontology of Gene Sets (ZEOGS): a tool to analyze enrichment of zebrafish anatomical terms in large gene sets. Zebrafish, 10(3), 303-315. doi:10.1089/zeb.2012.0865. [PubMan] : Ziv, L., Muto, A., Schoonheim, P. J., Meijsing, S. H., Strasser, D., Ingraham, H. A., Schaaf, M. J., Yamamoto, K. R., & Baier, H. (2012). An affective disorder in zebrafish with mutation of the glucocorticoid receptor. Molecular Psychiatry, 18(6), 681-91. doi:10.1038/mp.2012.64. [PubMan] : DeKelver, R. C., Choi, V. M., Moehle, E. A., Paschon, D. E., Hockemeyer, D., Meijsing, S. H., Sancak, Y., Cui, X., Steine, E. J., Miller, J. C., Tam, P., Bartsevich, V. V., Meng, X., Rupniewski, I., Gopalan, S. M., Sun, H. C., Pitz, K. J., Rock, J. M., Zhang, L., Davis, G. D., Rebar, E. J., Cheeseman, I. M., Yamamoto, K. R., Sabatini, D. M., Jaenisch, R., Gregory, P. D., & Urnov, F. D. (2010). Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome. Genome Research, 20(8), 1133-1142. [PubMan] : Barduhn, A., Ehrenhofer-Murray, A. E., Geissenhöner, A., Grünweller, A., Irlbacher, H., Kasulke, D., Marchfelder, U., Meijsing, S. H., Schaper, S., & Seitz, S. (2002). Mechanismen der transkriptionellen Genrepression in der Hefe Saccharomyces cerevisiae. In G. der Max-Planck-Gesellschaft (Ed.), Jahrbuch der Max-Planck-Gesellschaft (pp. 175-178). Göttingen: Vandenhoeck & Ruprecht. [PubMan]