Researcher Portfolio
Sperl, Bianca
Jungmann, Ralf / Molecular Imaging and Bionanotechnology, Max Planck Institute of Biochemistry, Max Planck Society, Ullrich, Axel / Molecular Biology, Max Planck Institute of Biochemistry, Max Planck Society
Researcher Profile
Position: Jungmann, Ralf / Molecular Imaging and Bionanotechnology, Max Planck Institute of Biochemistry, Max Planck Society
Position: Ullrich, Axel / Molecular Biology, Max Planck Institute of Biochemistry, Max Planck Society
Researcher ID: https://pure.mpg.de/cone/persons/resource/persons78730
Publications
(1 - 25 of 77)
: Di Matteo, F., Bonrath, R., Pravata, V., Schmidt, H., Ayo-Martin, A. C., Di Giaimo, R., Menegaz, D., Riesenberg, S., de Vrij, F. M. S., Maccarrone, G., Holzapfel, M., Straub, T., Kushner, S. A., Robertson, S. P., Eder, M., & Cappello, S. (2025). Neuronal hyperactivity in neurons derived from individuals with gray matter heterotopia. NATURE COMMUNICATIONS, 16(1): 1737. doi:10.1038/s41467-025-56998-1. [PubMan] : van Doeselaar, L., Abromeit, A., Stark, T., Menegaz, D., Ballmann, M., Mitra, S., Yang, H., Rehawi, G., Huettl, R. E., Bordes, J., Narayan, S., Harbich, D., Deussing, J. M., Rammes, G., Czisch, M., Knauer-Arloth, J., Eder, M., Lopez, J. P., & Schmidt, M. V. (2025). FKBP51 in glutamatergic forebrain neurons promotes early life stress inoculation in female mice. Nature communications, 16(1): 2529. doi:10.1038/s41467-025-57952-x. [PubMan] : Sen, P., Ortiz, O., Brivio, E., Menegaz, D., Sotillos Elliott, L., Du, Y., Ries, C., Chen, A., Wurst, W., Lopez, J. P., Eder, M., & Deussing, J. M. (2025). A bipolar disorder-associated missense variant alters adenylyl cyclase 2 activity and promotes mania-like behavior. MOLECULAR PSYCHIATRY, 30(1), 97-110. doi:10.1038/s41380-024-02663-w. [PubMan] : Raabe, F. J., Hausruckinger, A., Gagliardi, M., Ahmad, R., Almeida, V., Galinski, S., Hoffmann, A., Weigert, L., Rummel, C. K., Murek, V., Trastulla, L., Jiménez-Barrón, L., Atella, A., Maidl, S., Menegaz, D., Hauger, B., Wagner, E.-M., Gabellini, N., Kauschat, B., Riccardo, S., Cesana, M., Papiol, S., Sportelli, V., Rex-Haffner, M., Stolte, S. J., Wehr, M. C., Salcedo, T. O., Papazova, I., Detera-Wadleigh, S., McMahon, F. J., Schmitt, A., Falkai, P., Hasan, A., Cacchiarelli, D., Dannlowski, U., Nenadic, I., Kircher, T., Scheuss, V., Eder, M., Binder, E. B., Spengler, D., Rossner, M. J., & Ziller, M. J. (2024). Polygenic risk for schizophrenia converges on alternative polyadenylation as molecular mechanism underlying synaptic impairment. bioRxiv: the preprint server for biology. doi:10.1101/2024.01.09.574815. [PubMan] : Loganathan, S., Menegaz, D., Delling, J.-P., Eder, M., & Deussing, J. M. (2024). <i>Cacna1c</i> deficiency in forebrain glutamatergic neurons alters behavior and hippocampal plasticity in female mice. TRANSLATIONAL PSYCHIATRY, 14(1): 421. doi:10.1038/s41398-024-03140-2. [PubMan] : Rummel, C., Gagliardi, M., Ahmad, R., Herholt, A., Jiménez-Barrón, L., Murek, V., Weigert, L., Hausruckinger, A., Maidl, S., Hauger, B., Raabe, F. J., Fuerle, C., Trastulla, L., Turecki, G., Eder, M., Rossner, M. J., & Ziller, M. J. (2023). Massively parallel functional dissection of schizophrenia- associated noncoding genetic variants. CELL, 186(23), 5165-5182.e33. doi:10.1016/j.cell.2023.09.015. [PubMan] : Lopez, J. P., Luecken, M. D., Brivio, E., Karamihalev, S., Kos, A., De Donno, C., Benjamin, A., Yang, H., Dick, A. L. W., Stoffel, R., Flachskamm, C., Ressle, A., Roeh, S., Huettl, R. E., Parl, A., Eggert, C., Novak, B., Yan, Y., Yeoh, K., Lebar, M., Hauger, B., Harbich, D., Schmid, B., Di Giaimo, R., Turck, C. W., Schmidt, M. V., Deussing, J. M., Eder, M., Dine, J., Theis, F. J., & Chen, A. (2022). Ketamine exerts its sustained antidepressant effects via cell-type-specific regulation of Kcnq2. NEURON, 110(14), 2283-2298.e9. doi:10.1016/j.neuron.2022.05.001. [PubMan] : Chang, S., Fermani, F., Lao, C.-L., Huang, L., Jakovcevski, M., Di Giaimo, R., Gagliardi, M., Menegaz, D., Hennrich, A. A., Ziller, M., Eder, M., Klein, R., Cai, N., & Deussing, J. M. (2022). Tripartite extended amygdala-basal ganglia CRH circuit drives locomotor activation and avoidance behavior. SCIENCE ADVANCES, 8(46). doi:10.1126/sciadv.abo1023. [PubMan] : Hausl, A. S., Brix, L., Hartmann, J., Poehlmann, M. L., Lopez, J. P., Menegaz, D., Brivio, E., Engelhardt, C., Roeh, S., Bajaj, T., Rudolph, L., Stoffel, R., Hafner, K., Goss, H. M., Reul, J. M. H. M., Deussing, J. M., Eder, M., Ressler, K. J., Gassen, N. C., Chen, A., & Schmidt, M. V. (2021). The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus of male mice. MOLECULAR PSYCHIATRY. doi:10.1038/s41380-021-01044-x. [PubMan] : Schraut, K.-G., Kalnytska, O., Lamp, D., Jastroch, M., Eder, M., Hausch, F., Gassen, N. C., Moore, S., Nagaraj, N., Lopez, J. P., Chen, A., & Schmidt, M. V. (2021). Loss of the psychiatric risk factor SLC6A15 is associated with increased metabolic functions in primary hippocampal neurons. EUROPEAN JOURNAL OF NEUROSCIENCE, 53(2), 390-401. doi:10.1111/ejn.14990. [PubMan] : Engel, M., Eggert, C., Kaplick, P. M., Eder, M., Röh, S., Tietze, L., Namendorf, C., Arloth, J., Weber, P., Rex-Haffner, M., Geula, S., Jakovcevski, M., Hanna, J. H., Leshkowitz, D., Uhr, M., Wotjak, C. T., Schmidt, M. V., Deussing, J. M., Binder, E. B., & Chen, A. (2018). The Role of m6A/m-RNA Methylation in Stress Response Regulation. NEURON, 99(2), 389-403. doi:10.1016/j.neuron.2018.07.009. [PubMan] : Dedic, N., Poehlmann, M. L., Richter, J. S., Mehta, D., Czamara, D., Metzger, M. W., Dine, J., Bedenk, B. T., Hartmann, J., Wagner, K. V., Jurik, A., Almli, L. M., Lori, A., Moosmang, S., Hofmann, F., Wotjak, C. T., Rammes, G., Eder, M., Chen, A., Ressler, K. J., Wurst, W., Schmidt, M. V., Binder, E. B., & Deussing, J. M. (2018). Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood. MOLECULAR PSYCHIATRY, 23(3), 533-543. doi:10.1038/mp.2017.133. [PubMan] : Micale, V., Stepan, J., Jurik, A., Pamplona, F. A., Marsch, R., Drago, F., Eder, M., & Wotjak, C. T. (2017). Extinction of avoidance behavior by safety learning depends on endocannabinoid signaling in the hippocampus. JOURNAL OF PSYCHIATRIC RESEARCH, 90, 46-59. doi:10.1016/j.jpsychires.2017.02.002. [PubMan] : Rein, T., Stepan, J., Balsevich, G., Hartmann, J., Genewsky, A., Hafner, K., Schmidt, M. V., Eder, M., & Gassen, N. (2017). Novel route to autophagy links to synaptic function and treatment options in depression. EUROPEAN NEUROPSYCHOPHARMACOLOGY, 27: S.05.04, S530-S530. [PubMan] : Henckens, M. J. A. G., Printz, Y., Shamgar, U., Dine, J., Lebow, M., Drori, Y., Kuehne, C., Kolarz, A., Eder, M., Deussing, J. M., Justice, N. J., Yizhar, O., & Chen, A. (2017). CRF receptor type 2 neurons in the posterior bed nucleus of the stria terminalis critically contribute to stress recovery. MOLECULAR PSYCHIATRY, 22(12), 1691-1700. doi:10.1038/mp.2016.133. [PubMan] : Shemesh, Y., Forkosh, O., Mahn, M., Anpilov, S., Sztainberg, Y., Manashirov, S., Shlapobersky, T., Elliott, E., Tabouy, L., Ezra, G., Adler, E., Ben-Efraim, Y. J., Shosh, G., Kuperman, Y., Haramati, S., Dine, J., Eder, M., Deussing, J. M., Schneidman, E., Yizhar, O., & Chen, A. (2016). Ucn3 and CRF-R2 in the medial amygdala regulate complex social dynamics. NATURE NEUROSCIENCE, 19(11), 1489-1496. doi:10.1038/nn.4346. [PubMan] : Kuperman, Y., Weiss, M., Dine, J., Staikin, K., Golani, O., Ramot, A., Nahum, T., Kuehne, C., Shemesh, Y., Wurst, W., Harmelin, A., Deussing, J. M., Eder, M., & Chen, A. (2016). CRFR1 in AgRP Neurons Modulates Sympathetic Nervous System Activity to Adapt to Cold Stress and Fasting. CELL METABOLISM, 23(6), 1185-1199. doi:10.1016/j.cmet.2016.04.017. [PubMan] : Dine, J., Genewsky, A., Hladky, F., Wotjak, C. T., Deussing, J. M., Zieglgänsberger, W., Chen, A., & Eder, M. (2016). Corrigendum: Local Optogenetic Induction of Fast (20-40Hz) Pyramidal-Interneuron Network Oscillations in the In Vitro and In Vivo CA1 Hippocampus: Modulation by CRF and Enforcement of Perirhinal Theta Activity. FRONTIERS IN CELLULAR NEUROSCIENCE, 10: 148. doi:10.3389/fncel.2016.00148. [PubMan] : Tanasic, S., Mattusch, C., Wagner, E.-M., Eder, M., Rupprecht, R., Rammes, G., & Di Benedetto, B. (2016). Desipramine targets astrocytes to attenuate synaptic plasticity via modulation of the ephrinA3/EphA4 signalling. NEUROPHARMACOLOGY, 105, 154-163. doi:10.1016/j.neuropharm.2016.01.021. [PubMan] : Dine, J., Genewsky, A., Hladky, F., Wotjak, C. T., Deussing, J. M., Zieglgaensberger, W., Chen, A., & Eder, M. (2016). Local Optogenetic Induction of Fast (20-40 Hz) Pyramidal-Interneuron Network Oscillations in the In Vitro and In Vivo CA1 Hippocampus: Modulation by CRF and Enforcement of Perirhinal Theta Activity. FRONTIERS IN CELLULAR NEUROSCIENCE, 10: 108. doi:10.3389/fncel.2016.00108. [PubMan] : Stepan, J., Hladky, F., Uribe, A., Holsboer, F., Schmidt, M. V., & Eder, M. (2015). High-Speed imaging reveals opposing effects of chronic stress and antidepressants on neuronal activity propagation through the hippocampal trisynaptic circuit. FRONTIERS IN NEURAL CIRCUITS, 9: 70. doi:10.3389/fncir.2015.00070. [PubMan] : Dine, J., Ionescu, I., Avrabos, C., Yen, Y.-C., Holsboer, F., Landgraf, R., Schmidt, U., & Eder, M. (2015). Intranasally Applied Neuropeptide S Shifts a High-Anxiety Electrophysiological Endophenotype in the Ventral Hippocampus towards a "Normal"-Anxiety One. PLOS ONE, 10(4): e0120272. doi:10.1371/journal.pone.0120272. [PubMan] : Stepan, J., Dine, J., & Eder, M. (2015). Functional optical probing of the hippocampal trisynaptic circuit in vitro: network dynamics, filter properties, and polysynaptic induction of CA1 LTP. Frontiers in neuroscience, 9: 160. doi:10.3389/fnins.2015.00160. [PubMan] : Cuboni, S., Devigny, C., Hoogeland, B., Strasser, A., Pomplun, S., Hauger, B., Hoefner, G., Wanner, K. T., Eder, M., Buschauer, A., Holsboer, F., & Hausch, F. (2014). Loratadine and Analogues: Discovery and Preliminary Structure-Activity Relationship of Inhibitors of the Amino Acid Transporter B(0)AT2. JOURNAL OF MEDICINAL CHEMISTRY, 57(22), 9473-9479. doi:10.1021/jm501086v. [PubMan] : Gassen, N. C., Hartmann, J., Zschocke, J., Stepan, J., Hafner, K., Zellner, A., Kirmeier, T., Kollmannsberger, L., Wagner, K. V., Dedic, N., Balsevich, G., Deussing, J. M., Kloiber, S., Lucae, S., Holsboer, F., Eder, M., Uhr, M., Ising, M., Schmidt, M. V., & Rein, T. (2014). Association of FKBP51 with Priming of Autophagy Pathways and Mediation of Antidepressant Treatment Response: Evidence in Cells, Mice, and Humans. PLOS MEDICINE, 11(11): e1001755. doi:10.1371/journal.pmed.1001755. [PubMan]