Researcher Portfolio

Stegle, Oliver

Department Molecular Biology, Max Planck Institute for Developmental Biology, Max Planck Society, Former Research Group Machine Learning and Computational Biology, Max Planck Institute for Biological Cybernetics, Max Planck Society, Rätsch Group, Friedrich Miescher Laboratory, Max Planck Society, Research Group Machine Learning and Computational Biology, Max Planck Institute for Intelligent Systems, Max Planck Society

Researcher Profile

Position: Former Research Group Machine Learning and Computational Biology, Max Planck Institute for Biological Cybernetics, Max Planck Society

Position: Department Molecular Biology, Max Planck Institute for Developmental Biology, Max Planck Society

Position: Rätsch Group, Friedrich Miescher Laboratory, Max Planck Society

Position: Research Group Machine Learning and Computational Biology, Max Planck Institute for Intelligent Systems, Max Planck Society

Additional IDs: ORCID: https://orcid.org/0000-0002-8818-7193
MPIKYB: stegle

Researcher ID: https://pure.mpg.de/cone/persons/resource/persons84969

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Publications

(1 - 25 of 117)

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: Cheung, S., Bredikhin, D., Gerber, T., Steenbergen, B., Basu, S., Bailleul, R., Hansen, P., Paix, A., Benton, M., Korswagen, H., Arendt, D., Stegle, O., & Ikmi, A. (2025). Systemic coordination of whole-body tissue remodeling during local regeneration in sea anemones. Developmental Cell, 60(5), 780-793. doi:10.1016/j.devcel.2024.11.001. [PubMan] : Beierholm, U., Rohe, T., Ferrari, A., Stegle, O., & Noppeney, U. (2020). Using the past to estimate sensory uncertainty. eLife, 9: e54172. doi:10.7554/eLife.54172. [PubMan] : Beierholm, U., Rohe, T., Ferrari, A., Stegle, O., & Noppeney, U. (2020). Using the past to estimate sensory uncertainty. eLife, 1-42. doi:10.7554/eLife.54172. [PubMan] : Lehmann, K., Kahles, A., Toussaint, N., Hüser, M., Stark, S., Sachsenberg, T., Stegle, O., Kohlbacher, O., Sander, C., & Rätsch, G. (2018). Comprehensive analysis of alternative splicing across tumors from 8,705 patients. In 68th Annual Meeting of the American Society of Human Genetics (ASHG 2018) (pp. 186). [PubMan] : Kahles, A., Lehmann, K.-V., Toussaint, N., Hüser, M., Sachsenberg, T., Stegle, O., Kohlbacher, O., Sander, C., Cancer Genome Atlas Research Network, & Rätsch, G. (2018). Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients. Cancer Cell, 34(2), 211-224. doi:10.1016/j.ccell.2018.07.001. [PubMan] : Ibrahim-Verbaas, C., Bressler, J., Debette, S., Schuur, M., Smith, A., Bis, J., Davies, G., Trompet, S., Smith, J., Wolf, C., Chibnik, L., Liu, Y., Vitart, V., Kirin, M., Petrovic, K., Polasek, O., Zgaga, L., Fawns-Ritchie, C., Hoffmann, P., Karjalainen, J., Lahti, J., Llewellyn, D., Schmidt, C., Mather, K., Chouraki, V., Sun, Q., Resnick, S., Rose, L., Oldmeadow, C., Stewart, M., Smith, B., Gudnason, V., Yang, Q., Mirza, S., Jukema, J., Dejager, P., Harris, T., Liewald, D., Amin, N., Coker, L., Stegle, O., Lopez, O., Schmidt, R., Teumer, A., Ford, I., Karbalai, N., Becker, J., Jonsdottir, M., Au, R., Fehrmann, R., Herms, S., Nalls, M., Zhao, W., Turner, S., Yaffe, K., Lohman, K., van Swieten, J., Kardia, S., Knopman, D., Meeks, W., Heiss, G., Holliday, E., Schofield, P., Tanaka, T., Stott, D., Wang, J., Ridker, P., Gow, A., Pattie, A., Starr, J., Hocking, L., Armstrong, N., McLachlan, S., Shulman, J., Pilling, L., Eiriksdottir, G., Scott, R., Kochan, N., Palotie, A., Hsieh, Y.-C., Eriksson, J., Penman, A., Gottesman, R., Oostra, B., Yu, L., DeStefano, A., Beiser, A., Garcia, M., Rotter, J., Noethen, M., Hofman, A., Slagboom, P., Westendorp, R., Buckley, B., Wolf, P., Uitterlinden, A., Psaty, B., Grabe, H., Bandinelli, S., Chasman, D., Grodstein, F., Roikkonen, K., Lambert, J.-C., Porteous, D., Price, J., Sachdev, P., Ferrucci, L., Attia, J., Rudan, I., Hayward, C., Wright, A., Wilson, J., Cichon, S., Franke, L., Schmidt, H., Ding, J., de Craen, A., Fornage, M., Bennett, D., Deary, I., Ikram, M., Launer, L., Fitzpatrick, A., Seshadri, S., van Duijn, C., & Mosley, T. (2016). GWAS for executive function and processing speed suggests involvement of the CADM2 gene. Molecular Psychiatry, 21(2), 189-197. doi:10.1038/mp.2015.37. [PubMan] : Beierholm, U., Rohe, T., Stegle, O., & Noppeney, U. (2016). Using the past to estimate sensory uncertainty. Poster presented at Computational and Systems Neuroscience Meeting (COSYNE 2016), Salt Lake City, UT, USA. [PubMan] : Beierholm, U., Rohe, T., Stegle, O., & Noppeney, U. (2016). Using the past to estimate sensory uncertainty. Poster presented at Computational and Systems Neuroscience Meeting (COSYNE 2016), Salt Lake City, UT, USA. [PubMan] : Dubin, M., Zhang, P., Meng, D., Remigereau, M.-S., Osborne, E., Casale, F., Drewe, P., Kahles, A., Jean, G., Vilhjálmsson, B., Jagoda, J., Irez, S., Voronin, V., Song, Q., Long, Q., Rätsch, G., Stegle, O., Clark, R., & Nordborg, M. (2015). DNA methylation in Arabidopsis has a genetic basis and shows evidence of local adaptation. eLife, 4: e05255. doi:10.7554/eLife.05255. [PubMan] : Debette, S., Verbaas, C., Bressler, J., Schuur, M., Smith, A., Bis, J., Davies, G., Wolf, C., Gudnason, V., Chibnik, L., Yang, Q., deStefano, A., de Quervain, D., Srikanth, V., Lahti, J., Grabe, H., Smith, J., Priebe, L., Yu, L., Karbalai, N., Hayward, C., Wilson, J., Campbell, H., Petrovic, K., Fornage, M., Chauhan, G., Yeo, R., Boxall, R., Becker, J., Stegle, O., Mather, K., Chouraki, V., Sun, Q., Rose, L., Resnick, S., Oldmeadow, C., Kirin, M., Wright, A., Jonsdottir, M., Au, R., Becker, A., Amin, N., Nalls, M., Turner, S., Kardia, S., Oostra, B., Windham, G., Coker, L., Zhao, W., Knopman, D., Heiss, G., Griswold, M., Gottesman, R., Vitart, V., Hastie, N., Zgaga, L., Rudan, I., Polasek, O., Holliday, E., Schofield, P., Choi, S., Tanaka, T., An, Y., Perry, R., Kennedy, R., Sale, M., Wang, J., Wadley, V., Liewald, D., Ridker, P., Gow, A., Pattie, A., Starr, J., Porteous, D., Liu, X., Thomson, R., Armstrong, N., Eiriksdottir, G., Assareh, A., Kochan, N., Widen, E., Palotie, A., Hsieh, Y.-C., Eriksson, J., Vogler, C., van Swieten, J., Shulman, J., Beiser, A., Rotter, J., Schmidt, C., Hoffmann, W., Noethen, M., Ferrucci, L., Attia, J., Uitterlinden, A., Amouyel, P., Dartigues, J.-F., Amieva, H., Raeikkoenen, K., Garcia, M., Wolf, P., Hofman, A., Longstreth Jr., W., Psaty, B., Boerwinkle, E., DeJager, P., Sachdev, P., Schmidt, R., Breteler, M., Teumer, A., Lopez, A., Cichon, S., Chasman, D., Grodstein, F., Müller-Myhsok, B., Tzourio, C., Papassotiropoulos, A., Bennett, D., Ikram, M., Deary, I., van Duijn, C., Launer, L., Fitzpatrick, A., Seshadri, S., & Mosley Jr., T. (2015). Genome-wide Studies of Verbal Declarative Memory in Nondemented Older People: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. Biological Psychiatry, 77(8), 749-763. doi:10.1016/j.biopsych.2014.08.027. [PubMan] : Hagmann, J., Becker, C., Müller, J., Stegle, O., Meyer, R., Wang, G., Schneeberger, K., Fitz, J., Altmann, T., Bergelson, J., Borgwardt, K., & Weigel, D. (2015). Century-scale Methylome Stability in a Recently Diverged Arabidopsis thaliana Lineage. PLoS Genetics, 11(1): e1004920. doi:10.1371/journal.pgen.1004920. [PubMan] : Cubillos, F., Stegle, O., Grondin, C., Canut, M., Tisné, G., & Loudet, O. (2014). Extensive cis-regulatory variation robust to environmental perturbation in Arabidopsis. Plant Cell, 26(11), 4298-4310. doi:10.1105/tpc.114.130310. [PubMan] : Cubillos, F., Stegle, O., Grondin, C., Canut, M., Tisné, G., & Loudet, O. (2014). Extensive cis-regulatory variation robust to environmental perturbation in Arabidopsis. Plant Cell, 26(11), 4298-4310. doi:10.1105/tpc.114.130310. [PubMan] : Lippert, C., Casale, F., Rakitsch, B., & Stegle, O. (submitted). LIMIX: genetic analysis of multiple traits. [PubMan] : Rakitsch, B., Lippert, C., Borgwardt, K., & Stegle, O. (2014). It is all in the noise: Efficient multi-task Gaussian process inference with structured residuals. In C. Burges, L. Bottou, M. Welling, Z. Ghahramani, & K. Weinberger (Eds.), Advances in Neural Information Processing Systems 26 (pp. 1468-1476). Red Hook, NY, USA: Curran. [PubMan] : Casale, F., Rakitsch, B., Lippert, C., & Stegle, O. (2013). A mixed-model approach for association studies of multiple variants to a set of correlated traits. In MLSB13: Seventh Workshop on Machine Learning in Systems Biology (pp. 33). [PubMan] : Ryberg, M., Sandberg, S., Mellberg, C., Stegle, O., Lindahl, B., Larsson, C., Hauksson, J., & Olsson, T. (2013). A Palaeolithic-type diet causes strong tissue-specific effects on ectopic fat deposition in obese postmenopausal women. Journal of Internal Medicine, 274(1), 67-76. doi:10.1111/joim.12048. [PubMan] : Fusi, N., Lippert, C., Borgwardt, K. M., Lawrence, N., & Stegle, O. (2013). Detecting regulatory gene-environment interactions with unmeasured environmental factors. Bioinformatics, 29(11), 1382-1389. doi:10.1093/bioinformatics/btt148. [PubMan] : Fusi, N., Lippert, C., Borgwardt, K., Lawrence, N., & Stegle, O. (2013). Detecting regulatory gene-environment interactions with unmeasured environmental factors. Bioinformatics, 29(11), 1382-1389. doi:10.1093/bioinformatics/btt148. [PubMan] : Drewe, P., Stegle, O., Hartmann, L., Kahles, A., Bohnert, R., Wachter, A., Borgwardt, K., & Rätsch, G. (2013). Accurate detection of differential RNA processing. Nucleic Acids Research, 41(10), 5189-5198. doi:10.1093/nar/gkt211. [PubMan] : Drewe, P., Stegle, O., Hartmann, L., Kahles, A., Bohnert, R., Wachter, A., Borgwardt, K. M., & Rätsch, G. (2013). Accurate detection of differential RNA processing. Nucleic Acids Research (London), 41(10), 5189-5198. doi:10.1093/nar/gkt211. [PubMan] : Drewe, P., Stegle, O., Hartmann, L., Kahles, A., Bohnert, R., Wachter, A., Borgwardt, K., & Rätsch, G. (2013). Accurate detection of differential RNA processing. Nucleic Acids Research, 41(10), 5189-5198. doi:10.1093/nar/gkt211. [PubMan] : Ryberg, M., Sandberg, S., Mellberg, C., Stegle, O., Lindahl, B., Larsson, C., Hauksson, J., & Olsson, T. (2013). A Palaeolithic-type diet causes strong tissue-specific effects on ectopic fat deposition in obese postmenopausal women. Journal of Internal Medicine, 274(1), 67-76. doi:10.1111/joim.12048. [PubMan] : Morris, Q., Brenner, S., Listgarten, J., & Stegle, O. (2013). The future of genome-based medicine. In R. Altman, A. Dunker, L. Hunter, T. Murray, & T. Klein (Eds.), Biocomputing 2013: Pacific Symposium on Biocomputing (pp. 456-458). Singapore: World Scientific Publishing Company. [PubMan] : Rakitsch, B., Lippert, C., Stegle, O., & Borgwardt, K. M. (2013). LMM-Lasso: A Lasso Multi-Marker Mixed Model for Association Mapping with Population Structure Correction. Bioinformatics, 29(2), 206-214. doi:10.1093/bioinformatics/bts669. [PubMan]