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  Identify the neural basis of vascular dynamic network connectivity with high-field fMRI

He, Y., Wang, M., Chen, X., & Yu, X. (2017). Identify the neural basis of vascular dynamic network connectivity with high-field fMRI. Poster presented at 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017), Honolulu, HI, USA.

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He, Y1, 2, Author           
Wang, M1, 2, Author           
Chen, X1, 2, Author           
Yu, X1, 2, Author           
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1Research Group Translational Neuroimaging and Neural Control, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528695              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: The vascular dynamic network connectivity was detected with the resting-state fMRI in rodent and human brains (abstract: 3115). However, the basis of vascular dynamic connectivity is unclear. Here, the GCaMP6-mediated calcium signal simultaneously detected by fiber optics with fMRI showed slow-freuqncy fluctuation (0.01-0.04Hz) correlated to the single-vessel fMRI signal fluctuation with lead times from 1 to 5 seconds. In addition, the correlation was observed on the slow-frequency oscillation of the power profile of the spontaneous calcium burst spikes with frequency bandwidth of 1-10Hz. Thus, the vascular dynamic network connectivity demonstrates the hemodynamic state changes coupled to the brain state fluctuation.

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 Dates: 2017-04-27
 Publication Status: Issued
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 Identifiers: BibTex Citekey: HeWCY2017
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Title: 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017)
Place of Event: Honolulu, HI, USA
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Title: 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 5288 Start / End Page: - Identifier: -