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  Fat perception in the human frontal operculum, insular and somatosensory cortex

Wistehube, T., Rullmann, M., Wiacek, C., Braun, P., & Pleger, B. (2018). Fat perception in the human frontal operculum, insular and somatosensory cortex. Scientific Reports, 8: 11825. doi:10.1038/s41598-018-30366-0.

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 Urheber:
Wistehube, Thomas1, 2, 3, Autor           
Rullmann, Michael1, 2, 3, 4, Autor           
Wiacek, Claudia5, 6, Autor
Braun, Peggy5, 6, Autor
Pleger, Burkhard1, 2, 3, 6, 7, 8, Autor           
Affiliations:
1Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, Leipzig, DE, ou_634549              
2Collaborative Research Center Obesity Mechanisms, Institute of Biochemistry, University of Leipzig, Germany, ou_persistent22              
3Integrated Research and Treatment Center Adiposity Diseases, University of Leipzig, Germany, ou_persistent22              
4Department of Nuclear Medicine, University of Leipzig, Germany, ou_persistent22              
5Center of Veterinary Public Health, University of Leipzig, Germany, ou_persistent22              
6BMBF nutriCARD, Center of Veterinary Public Health, University of Leipzig, Germany, ou_persistent22              
7Department of Neurology, University Hospital Bergmannsheil, Bochum, Germany, ou_persistent22              
8Collaborative Research Centre 874 “Integration and Representation of Sensory Processes”, Ruhr University, Bochum, Germany, ou_persistent22              

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 Zusammenfassung: Here, we combined magnetic resonance imaging with lesion-symptom mapping in patients with chronic brain lesions to investigate brain representations of sugar and fat perception. Patients and healthy controls rated chocolate milkshakes that only differed in sugar or fat content. As compared to controls, patients showed an impaired fat, but not sugar perception. Impairments in fat perception overlapped with the anterior insula and frontal operculum, together assumed to underpin gustatory processing. We also identified the mid-dorsal insula as well as the primary and secondary somatosensory cortex - regions previously assumed to integrate oral-sensory inputs. These findings suggest that fat perception involves a specific set of brain regions that were previously reported to underpin gustatory processing and oral-sensory integration processes.

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Sprache(n): eng - English
 Datum: 2018-03-072018-07-202018-08-07
 Publikationsstatus: Online veröffentlicht
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: DOI: 10.1038/s41598-018-30366-0
PMID: 30087417
PMC: PMC6081453
 Art des Abschluß: -

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Projektname : -
Grant ID : 01E01001
Förderprogramm : -
Förderorganisation : IFB Adiposity Diseases, German Federal Ministry of Education and Research (BMBF)
Projektname : Kompetenzcluster für Ernährung und kardiovaskuläre Gesundheit / nutriCARD
Grant ID : 01EA1808B
Förderprogramm : -
Förderorganisation : German Federal Ministry of Education and Research (BMBF)
Projektname : Obesity Mechanisms / SFB 1052
Grant ID : -
Förderprogramm : -
Förderorganisation : German Research Foundation (DFG)
Projektname : Integration and Representation of Sensory Processes / SFB 874
Grant ID : -
Förderprogramm : -
Förderorganisation : German Research Foundation (DFG)

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Titel: Scientific Reports
  Kurztitel : Sci. Rep.
Genre der Quelle: Zeitschrift
 Urheber:
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Ort, Verlag, Ausgabe: London, UK : Nature Publishing Group
Seiten: - Band / Heft: 8 Artikelnummer: 11825 Start- / Endseite: - Identifikator: ISSN: 2045-2322
CoNE: https://pure.mpg.de/cone/journals/resource/2045-2322