Entacapone and Tolcapone, two catechol-O-methyltransferase inhibitors (ICOMT), 
block fibril formation of {alpha}-synuclein and {beta}-amyloid and protect 
against amyloid-induced toxicity.

Di Giovanni, S.; Eleuteri, S.; Paleologou, K. E.; Yin, G.; Zweckstetter, M.; Carrupt, P. A.; Lashuel, H. A.

doi:10.1074/jbc.M109.080390

Local TagsRelease HistoryDetailsSummary

Entacapone and Tolcapone, two catechol-O-methyltransferase inhibitors (ICOMT), block fibril formation of {alpha}-synuclein and {beta}-amyloid and protect against amyloid-induced toxicity.

Di Giovanni, S., Eleuteri, S., Paleologou, K. E., Yin, G., Zweckstetter, M., Carrupt, P. A., et al. (2010). Entacapone and Tolcapone, two catechol-O-methyltransferase inhibitors (ICOMT), block fibril formation of {alpha}-synuclein and {beta}-amyloid and protect against amyloid-induced toxicity. Journal of Biological Chemistry, 285(20), 14941-14954. doi:10.1074/jbc.M109.080390.

Item is Released

show all hide all

Basic

show hide

Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0012-D59C-2 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0027-F39D-F

Genre: Journal Article

Files

show Files

hide Files

:

587693.pdf (Publisher version), 4MB

View Save

File Permalink:
https://hdl.handle.net/11858/00-001M-0000-0027-BD30-4

Name:
587693.pdf

Description:
-

OA-Status:

Visibility:
Public

MIME-Type / Checksum:
application/pdf / [MD5]

Technical Metadata:

View

Copyright Date:
-

Copyright Info:
-

License:
-

Locators

show

Creators

show

hide

Creators:
Di Giovanni, S., Author
Eleuteri, S., Author
Paleologou, K. E., Author
Yin, G.¹, Author
Zweckstetter, M.², Author
Carrupt, P. A., Author
Lashuel, H. A., Author

Affiliations:
1Department of NMR Based Structural Biology, MPI for biophysical chemistry, Max Planck Society, ou_578567
2Research Group of Protein Structure Determination using NMR, MPI for biophysical chemistry, Max Planck Society, ou_578571

Content

show

Details

show

hide

Language(s): eng - English

Dates: Date issued: 2010-05-14

Publication Status: Issued

Pages: -

Publishing info: -

Table of Contents: -

Rev. Type: Peer

Identifiers: eDoc: 450500
URI: http://www.jbc.org/content/285/20/14941.full.pdf+html?sid=68cd1005-d1c1-40a4-bea3-e289852e9444
DOI: 10.1074/jbc.M109.080390

Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show

hide

Title: Journal of Biological Chemistry

Source Genre: Journal

Creator(s):

Affiliations:

Publ. Info: -

Pages: - Volume / Issue: 285 (20) Sequence Number: - Start / End Page: 14941 - 14954 Identifier: -