ausblenden:
Schlagwörter:
alkaloids; biological activity; enzymes; inhibitors; phosphatases; prodigiosin
Zusammenfassung:
A common core. Protein phosphatases, such as the dual-specificity phosphatase VHR and the tyrosine phosphatase PTP1B, are key regulators of innumerable cellular processes, and new classes of phosphatase inhibitors are in demand. The azafulvene-containing core structures of the roseophilin and prodigiosin alkaloids define such a new class.
