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  Pre-fibrillar α-synuclein variants with impaired bold β-structure increase neurotoxicity in Parkinson's disease models.

Karpinar, P., Gajula Balija, M. B., Kügler, S., Opazo, F., Rezaei-Ghaleh, N., Wender, N., et al. (2009). Pre-fibrillar α-synuclein variants with impaired bold β-structure increase neurotoxicity in Parkinson's disease models. EMBO Journal, 28(20), 3256-3268. doi:10.1038/emboj.2009.257.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0012-D78E-1 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0028-97AE-B
Genre: Journal Article

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 Creators:
Karpinar, P.1, Author           
Gajula Balija, M. B.2, Author           
Kügler, S., Author
Opazo, F., Author
Rezaei-Ghaleh, N.1, Author           
Wender, N., Author
Kim, H. Y.1, Author           
Taschenberger, G., Author
Falkenburger, B. H., Author
Heise, H.3, Author           
Kumar, A.4, Author           
Riedel, D.5, Author           
Fichtner, L., Author
Voigt, A.2, Author           
Braus, G. H., Author
Giller, K.6, Author           
Becker, S.6, Author           
Herzig, A.2, Author           
Baldus, M.3, Author           
Jäckle, H.2, Author           
Eimer, S., AuthorSchulz, J. B., AuthorGriesinger, C.6, Author           Zweckstetter, M.1, Author            more..
Affiliations:
1Research Group of Protein Structure Determination using NMR, MPI for biophysical chemistry, Max Planck Society, ou_578571              
2Department of Molecular Developmental Biology, MPI for biophysical chemistry, Max Planck Society, ou_578590              
3Research Group of Solid State NMR Spectroscopy, MPI for biophysical chemistry, Max Planck Society, ou_persistent22              
4Research Group of Solid-State NMR, MPI for biophysical chemistry, Max Planck Society, ou_persistent35              
5Facility for Electron Microscopy, MPI for biophysical chemistry, Max Planck Society, ou_578615              
6Department of NMR Based Structural Biology, MPI for biophysical chemistry, Max Planck Society, ou_578567              

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Free keywords: neurodegeneration; oligomer; Parkinson's disease; structure; alpha-synuclein
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Language(s): eng - English
 Dates: 2009-09
 Publication Status: Issued
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 Rev. Type: Peer
 Identifiers: eDoc: 435911
URI: http://www.nature.com/emboj/journal/v28/n20/pdf/emboj2009257a.pdf
DOI: 10.1038/emboj.2009.257
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Title: EMBO Journal
Source Genre: Journal
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Pages: - Volume / Issue: 28 (20) Sequence Number: - Start / End Page: 3256 - 3268 Identifier: -