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Aged
Chromosome Aberrations/*radiation effects
Female
Humans
*In Situ Hybridization, Fluorescence
Male
*Nuclear Power Plants
Probability
*Radioactive Hazard Release
*Threshold Limit Values
Time Factors
Abstract:
Chromosome aberration (translocation) yield was investigated by mFISH in peripheral blood lymphocytes of Mayak Production Association (PA) workers with prolonged occupational exposure to ionizing radiation (IR). A dose threshold for cytogenetic indication of a prolonged occupational radiation exposure was estimated for Mayak PA workers using functions of dose distributions. Two limits were estimated for the indication of IR exposure to workers with a prolonged external gamma-ray exposure: These are a background translocation yield of N(0) = 0.812 +/- 0.149% and a dose threshold of indication D(0) estimated to be approximately 1 Gy.
