BCAT1 promotes cell proliferation through amino acid catabolism in gliomas 
carrying wild-type IDH1

Tönjes, Martje; Barbus, Sebastian; Park, Yoon Jung; Wang, Wei; Schlotter, Magdalena; Lindroth, Anders M.; Pleier, Sabrina V.; Bai, Alfa H.C.; Karra, Daniela; Piro, Rosario M.; Felsberg, Jörg; Addington, Adele; Lemke, Dieter; Weibrecht, Irene; Hovestadt, Volker; Rolli, Claudio G.; Campos, Benito; Turcan, Sevin; Sturm, Dominik; Witt, Hendrik; Chan, Timothy A.; Herold-Mende, Christel; Kemkemer, Ralf; König, Rainer; Schmidt, Kathrin; Hull, William-Edmund; Pfister, Stefan M.; Jugold, Manfred; Hutson, SusanM.; Plass, Christoph; Okun, Jürgen G.; Reifenberger, Guido; Lichter, Peter; Radlwimmer, Bernhard

doi:10.1038/nm.3217

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BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1

Tönjes, M., Barbus, S., Park, Y. J., Wang, W., Schlotter, M., Lindroth, A. M., et al. (2013). BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1. Nature Medicine, 19, 901-908. doi:10.1038/nm.3217.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0014-C5FD-3 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0014-C761-2

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Creators:
Tönjes, Martje¹, Author
Barbus, Sebastian¹, Author
Park, Yoon Jung^{2, 3}, Author
Wang, Wei¹, Author
Schlotter, Magdalena¹, Author
Lindroth, Anders M.², Author
Pleier, Sabrina V.^{1, 4}, Author
Bai, Alfa H.C.¹, Author
Karra, Daniela⁵, Author
Piro, Rosario M.^{6, 7}, Author
Felsberg, Jörg⁵, Author
Addington, Adele⁸, Author
Lemke, Dieter⁹, Author
Weibrecht, Irene¹, Author
Hovestadt, Volker¹, Author
Rolli, Claudio G.^{10, 11}, Author
Campos, Benito^{12, 13}, Author
Turcan, Sevin¹⁴, Author
Sturm, Dominik^{1, 4, 15}, Author
Witt, Hendrik^{1, 4, 15}, Author
Chan, Timothy A.¹⁴, AuthorHerold-Mende, Christel^{12, 13}, AuthorKemkemer, Ralf^{10, 11, 16}, Author König, Rainer^{6, 7}, AuthorSchmidt, Kathrin¹⁷, AuthorHull, William-Edmund¹⁸, AuthorPfister, Stefan M.^{1, 4, 15}, AuthorJugold, Manfred¹⁹, AuthorHutson, SusanM.⁸, AuthorPlass, Christoph², AuthorOkun, Jürgen G.¹⁷, AuthorReifenberger, Guido^{5, 20}, AuthorLichter, Peter¹, AuthorRadlwimmer, Bernhard¹, Author more..

Affiliations:
1Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, ou_persistent22
2Division of Epigenomics and Cancer Risk Factors, DKFZ, Heidelberg, ou_persistent22
3College of Health Science, Ewha Womans University, Seoul, South Korea, ou_persistent22
4Division of Pediatric Neurooncology, DKFZ, Heidelberg, ou_persistent22
5Department of Neuropathology, Heinrich Heine University, Düsseldorf, ou_persistent22
6nstitute of Pharmacy and Molecular Biotechnology and Bioquant, University of Heidelberg, Heidelberg, ou_persistent22
7Division of Theoretical Bioinformatics, DKFZ, Heidelberg, ou_persistent22
8Department of Human Nutrition, Foods and Exercise, Virginia Polytechnic Institute, Blacksburg, Virginia, USA, ou_persistent22
9Clinical Cooperation Unit Neurooncology, DKFZ, Heidelberg, ou_persistent22
10Dept. New Materials and Biosystems, Max Planck Institute for Intelligent Systems, Max Planck Society, ou_1497649
11Central Scientific Facility Biomaterials, Max Planck Institute for Intelligent Systems, Max Planck Society, ou_1497639
12Division of Experimental Neurosurgery, University of Heidelberg, Heidelberg, ou_persistent22
13Department of Neurosurgery, University of Heidelberg, Heidelberg, ou_persistent22
14Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA, ou_persistent22
15Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital, Heidelberg, ou_persistent22
16Reutlingen University of Applied Science, Reutlingen, ou_persistent22
17Department of General Pediatrics, Division of Inborn Metabolic Diseases, University Children's Hospital, Heidelberg, ou_persistent22
18Core Facility, Molecular Structural Analysis, DKFZ, Heidelberg, ou_persistent22
19Core Facility, Small Animal Imaging Center, DKFZ, Heidelberg, ou_persistent22
20German Cancer Consortium (DKTK), DKFZ, Heidelberg, ou_persistent22

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Free keywords: Abt. Spatz; ZWE Biomaterialien

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Language(s): eng - English

Dates: Date issued: 2013

Publication Status: Issued

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Rev. Type: Peer

Identifiers: DOI: 10.1038/nm.3217

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Title: Nature Medicine

Other : Nat. Med.

Source Genre: Journal

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Publ. Info: New York, NY : Nature Pub. Co.

Pages: - Volume / Issue: 19 Sequence Number: - Start / End Page: 901 - 908 Identifier: ISSN: 1078-8956
CoNE: https://pure.mpg.de/cone/journals/resource/954925606824