Deutsch
 
Hilfe Datenschutzhinweis Impressum
  DetailsucheBrowse

Datensatz

DATENSATZ AKTIONENEXPORT
  Changes of neural activity correlate with the severity of cortical ischemia in patients with unilateral major cerebral artery occlusion

Bundo, M., Inao, S., Nakamura, A., Kato, T., Ito, K., Tadokoro, M., et al. (2002). Changes of neural activity correlate with the severity of cortical ischemia in patients with unilateral major cerebral artery occlusion. Stroke, 33, 61-66.

Item is

Dateien

einblenden: Dateien
ausblenden: Dateien
:
bundo.pdf (beliebiger Volltext), 162KB
Name:
bundo.pdf
Beschreibung:
-
OA-Status:
Sichtbarkeit:
Öffentlich
MIME-Typ / Prüfsumme:
application/pdf / [MD5]
Technische Metadaten:
Copyright Datum:
-
Copyright Info:
eDoc_access: PUBLIC
Lizenz:
-

Externe Referenzen

einblenden:

Urheber

einblenden:
ausblenden:
 Urheber:
Bundo, M., Autor
Inao, S., Autor
Nakamura, Akinori1, Autor           
Kato, T., Autor
Ito, Koji, Autor
Tadokoro, M., Autor
Kabeya, R., Autor
Sugimoto, T., Autor
Kajita, Y., Autor
Yoshida, J., Autor
Affiliations:
1MPI of Cognitive Neuroscience (Leipzig, -2003), The Prior Institutes, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634574              

Inhalt

einblenden:
ausblenden:
Schlagwörter: Cerebral blood flow; Ischemia; Occlusion; Somatosensory evoked potentials
 Zusammenfassung: BACKGROUND AND PURPOSE: In major cerebral arterial steno-occlusive diseases, there can be remarkably decreased hemodynamic reserve without marked neurological impairments. In such settings, it is not known whether the neural activity is well maintained or disturbed according to the severity of cerebral ischemia. The present study was therefore undertaken to examine the neural activity under mild cerebral ischemia resulting from major cerebral arterial occlusion. METHODS: Seven patients with minor neurological impairment as well as either unilateral internal carotid artery or middle cerebral artery occlusion were studied. The severity of the cortical ischemia was assessed by measuring regional cerebral blood flow (rCBF) with positron emission tomography. The change in neural activity in the ischemic brain was then evaluated by means of somatosensory evoked magnetic field with magnetoencephalography. RESULTS: The rCBF in the primary sensory area and the strength of the initial component of somatosensory evoked magnetic field (N20 m) were significantly reduced (P<0.01) and the second component (P30 m) was significantly augmented (P<0.05) in the lesioned cerebral hemisphere as compared with the nonlesioned hemisphere. The asymmetry indexes for N20 m were positively correlated (r=0.78) and those for P30 m were inversely correlated (r=-0.92) with asymmetry indexes for rCBF. CONCLUSIONS: In patients with either unilateral internal carotid artery or middle cerebral artery occlusion and minor neural impairments, there was a reduction of afferent signal and an augmentation of the secondary response of the neurons in the primary sensory area. This showed correlation with the severity of cortical ischemia.

Details

einblenden:
ausblenden:
Sprache(n): eng - English
 Datum: 2002
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: -
 Identifikatoren: eDoc: 239229
Anderer: P6751
 Art des Abschluß: -

Veranstaltung

einblenden:

Entscheidung

einblenden:

Projektinformation

einblenden:

Quelle 1

einblenden:
ausblenden:
Titel: Stroke
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: Philadelphia, PA : Lippincott Williams & Wilkins
Seiten: - Band / Heft: 33 Artikelnummer: - Start- / Endseite: 61 - 66 Identifikator: ISSN: 0039-2499
CoNE: https://pure.mpg.de/cone/journals/resource/954925447729