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Free keywords:
Vesicle priming; Dos-response-curve; Nanodomaine; Readily releasable pool
Abstract:
Calcium ions regulate secretory processes in several ways. Most prominently they (i) trigger the release of vesicle contents rapidly and in a highly cooperative way and they (ii) control priming steps, which prepare vesicles for release. The importance of using assays with high time resolution for separating these distinct roles is pointed out here.
