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  Diffusion Tensor Imaging in ALS Compared with Proton MR Spectroscopy

Mader, I., Erb, M., Gleichmann, M., Schulz, J., Grodd, W., & Klose, U. (2003). Diffusion Tensor Imaging in ALS Compared with Proton MR Spectroscopy. Poster presented at 11th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2003), Toronto, ON, Canada.

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Mader, IK, Author
Erb, M1, Author              
Gleichmann, M, Author
Schulz, JB, Author
Grodd, W1, Author              
Klose, U, Author
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1External Organizations, ou_persistent22              

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 Abstract: Diffusion tensor imaging (DTI) may give information about the axonal impairment of the motor neurons in amyotrophic lateral sclerosis (ALS) by changes of the patterns of anisotropy, e.g. fractional anisotropy (FA). Proton MR spectroscopy is thought to provide surrogate markers for the axonal integrity. In this study, changes of FA were compared with spectral changes in identical anatomic regions (motor area - MA) of nine patients with ALS and ten healthy controls. In patients, choline and the FA were positively correlated, whereas the mean of the FA in the MA was not different between patients and controls.

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 Dates: 2003-07
 Publication Status: Published online
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Title: 11th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2003)
Place of Event: Toronto, ON, Canada
Start-/End Date: 2003-07-10 - 2003-07-16

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Title: 11th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2003)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 2624 Start / End Page: 490 Identifier: ISSN: 1545-4428