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Free keywords:
Organic Cation; Hydrophobic Core; Proximal Renal Tubule; Sulfate Transport; Tienilic Acid
Abstract:
If we consider the transport processes in the proximal renal tubule, this symposium deals with the majority of transport agencies which are present there (Fig. 1): The transporter for glucose, luminally Na+-dependent, contraluminally not so: the transporters for amino acids and for sulfate, again luminally Na+-dependent, contraluminally not; Na+-dependent transport processes for dicarboxylate at both cell sides; and then the two secretory systems a] for organic anions, contraluminally in exchange for α-ketoglutarate and luminally partially electrogenic, partially working as exchanger and b] for organic cations contraluminally driven by an electrogenic exchange and luminally driven by an H+-organic cation antiport.
