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  Uniform transitions of the general RNA polymerase II transcription complex.

Mayer, A., Lidschreiber, M., Siebert, M., Leike, K., Söding, J., & Cramer, P. (2010). Uniform transitions of the general RNA polymerase II transcription complex. Nature Structural and Molecular Biology, 17(10), 1272-1278. doi:10.1038/nsmb.1903.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0015-8216-5 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0028-48F1-1
Genre: Journal Article

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http://www.nature.com/nsmb/journal/v17/n10/pdf/nsmb.1903.pdf (Publisher version)
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 Creators:
Mayer, A., Author
Lidschreiber, M., Author
Siebert, M., Author
Leike, K., Author
Söding, J.1, Author           
Cramer, P.2, Author           
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1Research Group of Computational Biology, MPI for Biophysical Chemistry, Max Planck Society, ou_1933286              
2Department of Molecular Biology, MPI for Biophysical Chemistry, Max Planck Society, ou_1863498              

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 Abstract: The genome-wide occupancy profiles for yeast RNA polymerase II in different phosphorylated forms, as well as transcription factors, are presented. The resulting analysis captures a 5' transition in which initiation factors are replaced by a general set of elongation factors that form a productive complex, which disassembles in two steps at the 3' end of the gene.

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Language(s): eng - English
 Dates: 2010-09-05
 Publication Status: Published online
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 Rev. Type: Peer
 Identifiers: DOI: 10.1038/nsmb.1903
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Title: Nature Structural and Molecular Biology
Source Genre: Journal
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Pages: - Volume / Issue: 17 (10) Sequence Number: - Start / End Page: 1272 - 1278 Identifier: -