Macrocyclic statine-based inhibitors of BACE-1

Barazza, A.; Gotz, M.; Cadamuro, S. A.; Goettig, P.; Willem, M.; Steuber, H.; Kohler, T.; Jestel, A.; Reinemer, P.; Renner, C.; Bode, W.; Moroder, L.

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Macrocyclic statine-based inhibitors of BACE-1

Barazza, A., Gotz, M., Cadamuro, S. A., Goettig, P., Willem, M., Steuber, H., et al. (2007). Macrocyclic statine-based inhibitors of BACE-1. ChemBioChem, 8(17), 2078-2091.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0010-5E98-2 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0010-5E99-F

Genre: Journal Article

Alternative Title : ChemBioChem

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Creators:
Barazza, A.¹, Author
Gotz, M., Author
Cadamuro, S. A.¹, Author
Goettig, P.^{2, 3}, Author
Willem, M.¹, Author
Steuber, H., Author
Kohler, T., Author
Jestel, A., Author
Reinemer, P., Author
Renner, C.¹, Author
Bode, W.^{2, 3, 4}, Author
Moroder, L.⁵, Author

Affiliations:
1External Organizations, ou_persistent22
2Fässler, Reinhard / Molecular Medicine, Max Planck Institute of Biochemistry, Max Planck Society, ou_1565147
3Huber, Robert / Structure Research, Max Planck Institute of Biochemistry, Max Planck Society, ou_1565155
4Conti, Elena / Structural Cell Biology, Max Planck Institute of Biochemistry, Max Planck Society, ou_1565144
5Moroder, Luis / Bioorganic Chemistry, Max Planck Institute of Biochemistry, Max Planck Society, ou_1565160

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Free keywords: BACE-1 inhibitors; macrocycles; NMR conformation; synthesis; X-ray structures

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Language(s): eng - English

Dates: Date issued: 2007-11-23

Publication Status: Issued

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Rev. Type: Peer

Identifiers: eDoc: 334599
ISI: 000251280600009

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Title: ChemBioChem

Alternative Title : ChemBioChem

Source Genre: Journal

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Pages: - Volume / Issue: 8 (17) Sequence Number: - Start / End Page: 2078 - 2091 Identifier: ISSN: 1439-4227