English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
 
 
DownloadE-Mail
  Assembly and positioning of the oocyte meiotic spindle.

Mogessie, B., Scheffler, K., & Schuh, M. (2018). Assembly and positioning of the oocyte meiotic spindle. In R. Lehmann (Ed.), Annual Review of Cell and Developmental Biology (pp. 381-403). doi:10.1146/annurev-cellbio-100616-060553.

Item is

Files

show Files
hide Files
:
2627862.pdf (Publisher version), 3MB
 
File Permalink:
-
Name:
2627862.pdf
Description:
-
OA-Status:
Visibility:
Restricted ( Max Planck Society (every institute); )
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show

Creators

show
hide
 Creators:
Mogessie, B.1, Author           
Scheffler, K., Author
Schuh, M.1, Author           
Affiliations:
1Department of Meiosis, MPI for Biophysical Chemistry, Max Planck Society, ou_2205654              

Content

show
hide
Free keywords: -
 Abstract: Fertilizable eggs develop from diploid precursor cells termed oocytes. Once every menstrual cycle, an oocyte matures into a fertilizable egg in the ovary. To this end, the oocyte eliminates half of its chromosomes into a small cell termed a polar body. The egg is then released into the Fallopian tube, where it can be fertilized. Upon fertilization, the egg completes the second meiotic division, and the mitotic division of the embryo starts. This review highlights recent work that has shed light on the cytoskeletal structures that drive the meiotic divisions of the oocyte in mammals. In particular, we focus on how mammalian oocytes assemble a microtubule spindle in the absence of centrosomes, how they position the spindle in preparation for polar body extrusion, and how the spindle segregates the chromosomes. We primarily focus on mouse oocytes as a model system but also highlight recent insights from human oocytes. Expected final online publication date for the Annual Review of Cell and Developmental Biology Volume 34 is October 6, 2018. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

Details

show
hide
Language(s): eng - English
 Dates: 2018-07-202018-10
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Annual Review of Cell and Developmental Biology
Source Genre: Series
 Creator(s):
Lehmann, R., Editor
Affiliations:
-
Publ. Info: -
Pages: - Volume / Issue: 34 Sequence Number: - Start / End Page: 381 - 403 Identifier: -