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  Cardiac cycle-induced EPI time series fluctuations in the brain: Their temporal shifts, inflow effects and T2* fluctuations

Viessmann, O., Möller, H. E., & Jezzard, P. (2017). Cardiac cycle-induced EPI time series fluctuations in the brain: Their temporal shifts, inflow effects and T2* fluctuations. NeuroImage, 162, 93-105. doi:10.1016/j.neuroimage.2017.08.061.

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資料種別: 学術論文

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Viessmann_Möller_2017.pdf (出版社版), 3MB
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https://hdl.handle.net/21.11116/0000-0001-FD5A-E
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Viessmann_Möller_2017.pdf
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application/pdf / [MD5]
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 作成者:
Viessmann, Olivia1, 著者
Möller, Harald E.2, 著者           
Jezzard, Peter1, 著者
所属:
1Nuffield Department Clinical Neurosciences, FMRIB CentreUniversity of Oxford, United Kingdom, ou_persistent22              
2Methods and Development Unit Nuclear Magnetic Resonance, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634558              

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キーワード: Ultra-fast EPI; Multiband; Multi-echo; Cardiac pulsatility; Partial volume; Physiological noise; Cerebral compliance
 要旨: The cardiac-induced arterial pressure wave causes changes in cerebral blood flow velocities and volumes that affect the signals in echo-planar imaging (EPI). Using single-echo EPI time series data, acquired fast enough to unalias the cardiac frequency, we found that the cardiac cycle-induced signal fluctuations are delayed differentially in different brain regions. When referenced to the time series in larger arterial structures, the cortical voxels are only minimally shifted but significant shifts are observed in subcortical areas. Using double-echo EPI data we mapped the voxels’ “signal at zero echo time”, S0, and apparent View the MathML sourceT2∗ over the cardiac cycle. S0 pulsatility was maximised for voxels with a cardiac cycle-induced timing that was close to the arterial structures and is likely explained by enhanced inflow effects in the cortical areas compared to subcortical areas. Interestingly a consistent View the MathML sourceT2∗ waveform over the cardiac cycle was observed in all voxels with average amplitude ranges between 0.3-0.55% in grey matter and 0.15–0.22% in white matter. The timing of the View the MathML sourceT2∗ waveforms suggests a partial volume fluctuation where arteriolar blood volume changes are counterbalanced by changes in CSF volumes.

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言語: eng - English
 日付: 2017-08-172017-07-102017-08-252017-08-312017-11-15
 出版の状態: 出版
 ページ: -
 出版情報: -
 目次: -
 査読: 査読あり
 識別子(DOI, ISBNなど): DOI: 10.1016/j.neuroimage.2017.08.061
PMID: 28864026
PMC: PMC5711428
その他: Epub 2017
 学位: -

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Project information

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Project name : Ultra-High Field Magnetic Resonance Imaging / HIMR
Grant ID : 316716
Funding program : Funding Programme 7
Funding organization : European Commission (EC)
Project name : -
Grant ID : -
Funding program : -
Funding organization : National Institute for Health Research Oxford Biomedical Research Centre
Project name : -
Grant ID : 203139/Z/16/Z
Funding program : -
Funding organization : Wellcome Trust
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Funding program : -
Funding organization : The Dunhill Medical Trust
Project name : -
Grant ID : -
Funding program : -
Funding organization : University of Minnesota, Center for Magnetic Resonance Research

出版物 1

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出版物名: NeuroImage
種別: 学術雑誌
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出版社, 出版地: Orlando, FL : Academic Press
ページ: - 巻号: 162 通巻号: - 開始・終了ページ: 93 - 105 識別子(ISBN, ISSN, DOIなど): ISSN: 1053-8119
CoNE: https://pure.mpg.de/cone/journals/resource/954922650166