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Free keywords:
combinatorial chemistry; in vitro selection; matrix-assisted
laser desorption mass spectrometry; peptide-DNA hybrids;
porphyrins
Photodynamic therapy; modified oligonucleotides; genetic
algorithm; myoglobin; ionization; photosensitizers;
reconstitution; mechanism
Abstract:
Background: Selection experiments involving chemical libraries are routinely used in the pharmaceutical industry for finding and optimizing lead compounds, In principle, almost any process involving a binding event or a reaction could be probed systemat
