非表示:
キーワード:
Adenosinetriphosphatase/ge [Genetics]; Adenosinetriphosphatase/me [Metabolism]; *Archaea/en [Enzymology]; Archaea/ge [Genetics]; Archaea/ul [Ultrastructure]; *Bacteria/en [Enzymology]; Bacteria/ge [Genetics]; Bacteria/ul [Ultrastructure]; *Cysteine Endopeptidases/ge [Genetics]; *Cysteine Endopeptidases/me [Metabolism]; Endopeptidases/ge [Genetics]; *Endopeptidases/me [Metabolism]; *Multienzyme Complexes/ge [Genetics]; *Multienzyme Complexes/me [Metabolism]; Support, Non-U.S. Gov't
要旨:
The proteasome represents the major non-lysosomal proteolytic system in eukaryotes. It confines proteolytic activity to an inner compartment that is accessible to unfolded proteins only. The strategy of controlling intracellular breakdown of proteins by self-compartmentalization is also used by different types of prokaryotic energy-dependent proteases. Genomic sequencing data reveal that various combinations of these energy-dependent proteases occur in prokaryotic cells from different lineages. [References: 33]