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  Neandertal and Denisovan DNA from Pleistocene sediments

Slon, V., Hopfe, C., Weiß, C. L., Mafessoni, F., de la Rasilla, M., Lalueza-Fox, C., et al. (2017). Neandertal and Denisovan DNA from Pleistocene sediments. Science, 356(6338), 605-608. doi:10.1126/science.aam9695.

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 Creators:
Slon, Viviane1, 2, 3, Author           
Hopfe, Charlotte4, Author           
Weiß, Clemens L., Author
Mafessoni, Fabrizio2, Author           
de la Rasilla, Marco, Author
Lalueza-Fox, Carles, Author
Rosas, Antonio, Author
Soressi, Marie, Author
Knul, Monika V., Author
Miller, Rebecca, Author
Stewart, John R., Author
Derevianko, Anatoly P., Author
Jacobs, Zenobia, Author
Li, Bo, Author
Roberts, Richard G., Author
Shunkov, Michael V., Author
de Lumley, Henry, Author
Perrenoud, Christian, Author
Gušic, Ivan, Author
Kucan, Željko, Author
Rudan, Pavao, AuthorAyinuer-Petri, Aximu2, 4, Author           Essel, Elena2, 4, AuthorNagel, Sarah2, 4, Author           Nickel, Birgit2, Author           Schmidt, Anna2, 4, AuthorPrüfer, Kay2, 5, Author           Kelso, Janet2, 6, Author           Burbano, Hernán A.2, Author           Pääbo, Svante1, 2, Author           Meyer, Matthias2, 4, Author more..
Affiliations:
1Neandertals and more, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society, ou_2074328              
2Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society, ou_1497672              
3The Leipzig School of Human Origins (IMPRS), Max Planck Institute for Evolutionary Anthropology, Max Planck Society, Deutscher Platz 6, 04103 Leipzig, DE, ou_1497688              
4Advanced DNA Sequencing Techniques, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society, ou_2074332              
5Genomes, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society, ou_2074331              
6The Minerva Research Group for Bioinformatics, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society, ou_2074303              

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 Abstract: Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples we detect Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility to detect the presence of hominin groups at sites and in areas where no skeletal remains are found.

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Language(s): eng - English
 Dates: 2017-04-272017-05-12
 Publication Status: Issued
 Pages: 13
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1126/science.aam9695
 Degree: -

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Grant ID : 694707
Funding program : Horizon 2020 (H2020)
Funding organization : European Commission (EC)

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Title: Science
Source Genre: Journal
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Publ. Info: Washington, D.C. : American Association for the Advancement of Science
Pages: - Volume / Issue: 356 (6338) Sequence Number: - Start / End Page: 605 - 608 Identifier: ISSN: 0036-8075
CoNE: https://pure.mpg.de/cone/journals/resource/991042748276600_1