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  Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging

Gündüz, S., Savić, T., Toljić, Đ., & Angelovski, G. (2016). Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging. Journal of Visualized Experiments, 2016(118), 1-10. doi:10.3791/54776.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0000-7943-D Version Permalink: https://hdl.handle.net/21.11116/0000-0003-9694-C
Genre: Journal Article

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226353/pdf/jove-118-54776.pdf (Any fulltext)
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 Creators:
Gündüz, S1, 2, Author           
Savić, T1, 2, Author           
Toljić, Đ1, 2, Author           
Angelovski, G1, 2, Author           
Affiliations:
1Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              
2Research Group MR Neuroimaging Agents, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528691              

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 Abstract: This protocol describes the preparation and characterization of a dendrimeric magnetic resonance imaging (MRI) contrast agent that carries cyclen-based macrocyclic chelates coordinating paramagnetic gadolinium ions. In a series of MRI experiments in vitro, this agent produced an amplified MRI signal when compared to the commercially available monomeric analogue.

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 Dates: 2016-04-12
 Publication Status: Published online
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 Rev. Type: -
 Identifiers: DOI: 10.3791/54776
BibTex Citekey: GunduzSTA2016
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Title: Journal of Visualized Experiments
Source Genre: Journal
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Pages: - Volume / Issue: 2016 (118) Sequence Number: - Start / End Page: 1 - 10 Identifier: eDoc: e54776
ISSN: 1940-087X