ausblenden:
Schlagwörter:
antibiotic biosynthesis; benzoic acid; marine bacterium; oxygenase; polyketide synthase
Phenylalanine ammonia-lyase; engineered biosynthesis; escherichia-coli; molecular characterization; nucleotide- sequence; starter unit; rhodopseudomonas-palustris; catalytic specificity; deduced functions; dna-sequence
Zusammenfassung:
Background: Polycyclic aromatic polyketides, such as the tetracyclines and anthracyclines, are synthesized by bacterial aromatic polyketide synthases (PKSs). Such PKSs contain a single set of iteratively used individual proteins for the construction of