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  Formation of COPI-coated vesicles at a glance.

Arakel, E. C., & Schwappach, B. (2018). Formation of COPI-coated vesicles at a glance. Journal of Cell Science, 131(5): 209890. doi:10.1242/jcs.209890.

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 Creators:
Arakel, E. C., Author
Schwappach, B.1, Author           
Affiliations:
1Max Planck Fellow Blanche Schwappach, ou_1548137              

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Free keywords: Arf1; ArfGAP; COPI; Coatomer; Endoplasmic reticulum; Golgi; Vesicle coat
 Abstract: The coat protein complex I (COPI) allows the precise sorting of lipids and proteins between Golgi cisternae and retrieval from the Golgi to the ER. This essential role maintains the identity of the early secretory pathway and impinges on key cellular processes, such as protein quality control. In this Cell Science at a Glance and accompanying poster, we illustrate the different stages of COPI-coated vesicle formation and revisit decades of research in the context of recent advances in the elucidation of COPI coat structure. By calling attention to an array of questions that have remained unresolved, this review attempts to refocus the perspectives of the field.

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Language(s): eng - English
 Dates: 2018-03-132018-03
 Publication Status: Issued
 Pages: -
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 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1242/jcs.209890
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Title: Journal of Cell Science
Source Genre: Journal
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Pages: 9 Volume / Issue: 131 (5) Sequence Number: 209890 Start / End Page: - Identifier: -