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  Two pockets in the active site of maize sesquiterpene synthase TPS4 carry out sequential parts of the reaction scheme resulting in multiple products

Köllner, T., O'Maille, P. E., Gatto, N., Boland, W., Gershenzon, J., & Degenhardt, J. (2006). Two pockets in the active site of maize sesquiterpene synthase TPS4 carry out sequential parts of the reaction scheme resulting in multiple products. Archives of Biochemistry and Biophysics, 448(1-2), 83-92. doi:10.1016/j.abb.2005.10.011.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0012-A694-7 Version Permalink: https://hdl.handle.net/21.11116/0000-0000-342D-4
Genre: Journal Article

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GER172.pdf (Publisher version), 0B
 
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 Creators:
Köllner, Tobias1, Author           
O'Maille, P. E., Author
Gatto, N.2, Author           
Boland, W.2, Author           
Gershenzon, J.1, Author           
Degenhardt, J.1, Author           
Affiliations:
1Department of Biochemistry, MPI for Chemical Ecology, Max Planck Society, ou_421893              
2Department of Bioorganic Chemistry, MPI for Chemical Ecology, Max Planck Society, ou_24028              

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Free keywords: Terpene synthase Sesquiterpene biosynthesis Multiproduct enzyme Terpene synthase reaction mechanism Directed mutagenesis Diphosphate synthase 5-epi-aristolochene synthase Monoterpene synthases Trichodiene synthase Bornyl diphosphate Swiss-model Terpene Biosynthesis Specificity Biochemistry & Biophysics in Current Contents(R)/Life Sciences
 Abstract: One of the most interesting features of terpene synthases is their ability to form multiple products with different carbon skeletons from a single prenyl diphosphate substrate. The maize sesquiterpene synthase TPS4, for example, produces a Mixture of 14

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 Dates: 2006
 Publication Status: Issued
 Pages: -
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 Rev. Type: -
 Identifiers: Other: GER172
DOI: 10.1016/j.abb.2005.10.011
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Title: Archives of Biochemistry and Biophysics
Source Genre: Journal
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Publ. Info: New York : Academic Press
Pages: - Volume / Issue: 448 (1-2) Sequence Number: - Start / End Page: 83 - 92 Identifier: ISSN: 0003-9861
CoNE: https://pure.mpg.de/cone/journals/resource/991042745826956