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  Dynamic changes of glutamate detected by functional MR spectroscopy in human visual cortex in regions with positive and negative BOLD response

Martínez-Maestro, M., Labadie, C., Giapitzakis, I., & Möller, H. (2017). Dynamic changes of glutamate detected by functional MR spectroscopy in human visual cortex in regions with positive and negative BOLD response. In 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017) (pp. 278-278).

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Item Permalink: https://hdl.handle.net/21.11116/0000-0000-C5B6-4 Version Permalink: https://hdl.handle.net/21.11116/0000-0000-F321-8
Genre: Meeting Abstract

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Martínez-Maestro, M, Author
Labadie, C, Author
Giapitzakis, I1, 2, 3, Author           
Möller, H, Author
Affiliations:
1Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_2528692              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              
3Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              

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 Abstract: Dynamic changes of metabolite concentrations have been presented in human visual cortex in response to stimulus that induce a positive BOLD response (PBR). The present study compares the metabolic profile of the positive and the negative bold response (NBR). The application of different fMRS block designs showed a significant increase in Glutamate (+7.3) during the PBR stimulation paradigm in agreement with previous studies and a decrease (-6.6) during the NBR, which provides new information about its underlaying mechanisms.

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 Dates: 2017-04-25
 Publication Status: Issued
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 Identifiers: BibTex Citekey: MartinezMaestroLGM2017
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Title: 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017)
Place of Event: Honolulu, HI, USA
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Title: 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 0404 Start / End Page: 278 - 278 Identifier: -