Features of Ras activation by a mislocalized oncogenic tyrosine kinase: FLT3 
ITD signals through K-Ras at the plasma membrane of acute myeloid leukemia cells

Köthe, Susanne; Müller, Jörg P.; Böhmer, Sylvia-Annette; Tschongov, Todor; Fricke, Melanie; Koch, Sina; Thiede, Christian; Requardt, Robert P.; Rubio, Ignacio; Böhmer, Frank D.

doi:10.1242/jcs.131789

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Features of Ras activation by a mislocalized oncogenic tyrosine kinase: FLT3 ITD signals through K-Ras at the plasma membrane of acute myeloid leukemia cells

Köthe, S., Müller, J. P., Böhmer, S.-A., Tschongov, T., Fricke, M., Koch, S., et al. (2013). Features of Ras activation by a mislocalized oncogenic tyrosine kinase: FLT3 ITD signals through K-Ras at the plasma membrane of acute myeloid leukemia cells. Journal of Cell Science, 126(20), 4746-4755. doi:10.1242/jcs.131789.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0014-B7D1-3 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0014-D049-4

Genre: Journal Article

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Creators:
Köthe, Susanne¹, Author
Müller, Jörg P.¹, Author
Böhmer, Sylvia-Annette¹, Author
Tschongov, Todor¹, Author
Fricke, Melanie¹, Author
Koch, Sina², Author
Thiede, Christian¹, Author
Requardt, Robert P.¹, Author
Rubio, Ignacio¹, Author
Böhmer, Frank D.¹, Author

Affiliations:
1External Organizations, ou_persistent22
2Abt. II: Systemische Zellbiologie, Max Planck Institute of Molecular Physiology, Max Planck Society, Otto-Hahn-Str. 11, 44227 Dortmund, DE, ou_1753288

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Free keywords: Oncogenic RTK, FLT3, FLT3 ITD, Leukemia, AML, Ras, Localization, Plasma membrane, Endomembrane

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Dates: Date issued: 2013-10-15

Publication Status: Issued

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Rev. Type: Peer

Identifiers: DOI: 10.1242/jcs.131789

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Title: Journal of Cell Science

Source Genre: Journal

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Publ. Info: Cambridge, UK : Co. of Biologists

Pages: - Volume / Issue: 126 (20) Sequence Number: - Start / End Page: 4746 - 4755 Identifier: ISSN: 0021-9533
CoNE: https://pure.mpg.de/cone/journals/resource/954925326678