ausblenden:
Schlagwörter:
aryl chloride - boron compounds - N-heterocyclic carbenes - palladium - Suzuki reaction
Zusammenfassung:
Through the use of Pd(OAc)2 and the sterically hindered imidazolium salt 5 (IPr · HCl) as the pre-catalyst mixture, aryl chlorides undergo efficient cross coupling reactions with 9-R-9-BBN derivatives (R = alkyl, allyl, alkynyl, cyclopropyl) in the presence of KOMe as the base. This procedure is easily scaleable and applies to electron poor and electron rich substrates with similar ease.
