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  Meta-populational demes constitute a reservoir for large MHC allele diversity in wild house mice (Mus musculus)

Linnenbrink, M., Teschke, M., Montero, I., Vallier, M., & Tautz, D. (2018). Meta-populational demes constitute a reservoir for large MHC allele diversity in wild house mice (Mus musculus). Frontiers in Zoology, 15: 15. doi:10.1186/s12983-018-0266-9.

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 Creators:
Linnenbrink, Miriam1, Author           
Teschke, Meike1, Author           
Montero, Inka1, Author           
Vallier, Marie2, Author           
Tautz, Diethard1, Author           
Affiliations:
1Department Evolutionary Genetics, Max Planck Institute for Evolutionary Biology, Max Planck Society, ou_1445635              
2Guest Group Evolutionary Genomics, Max Planck Institute for Evolutionary Biology, Max Planck Society, ou_1445638              

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Free keywords: Major histocompatibility complex; House mouse; Natural populations; Recombination; Reservoir model
 Abstract: The MHC class I and II loci mediate the adaptive immune response and belong to the most polymorphic loci in vertebrate genomes. In fact, the number of different alleles in a given species is often so large that it remains a challenge to provide an evolutionary model that can fully account for this.

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Language(s): eng - English
 Dates: 2018-03-012018-04-102018-04-202018-04
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1186/s12983-018-0266-9
BibTex Citekey: Linnenbrink2018
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Title: Frontiers in Zoology
Source Genre: Journal
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Publ. Info: London : BioMed Central
Pages: - Volume / Issue: 15 Sequence Number: 15 Start / End Page: - Identifier: ISSN: 1742-9994
CoNE: https://pure.mpg.de/cone/journals/resource/111090329096026