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  Antibiotic oxylipins from Alternanthera brasiliana and its endophytic bacteria

Almeida-Trapp, M., Kai, M., Mithöfer, A., & Rodrigues-Filho, E. (2015). Antibiotic oxylipins from Alternanthera brasiliana and its endophytic bacteria. Phytochemistry, 110, 72-82. doi:10.1016/j.phytochem.2014.11.005.

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 Creators:
Almeida-Trapp, Marilia1, Author              
Kai, Marco2, Author              
Mithöfer, Axel1, Author              
Rodrigues-Filho, Edson, Author
Affiliations:
1Department of Bioorganic Chemistry, Prof. Dr. W. Boland, MPI for Chemical Ecology, Max Planck Society, ou_24028              
2Research Group Mass Spectrometry, MPI for Chemical Ecology, Max Planck Society, ou_421899              

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 Abstract: Bioassay-guided fractionation of Alternanthera brasiliana stem extracts resulted in the isolation of an antibiotically active fraction. Five human pathogenic bacteria were used to guide the fractionation process for the isolation of antimicrobial compounds. Finally, 17 linoleate oxylipins were identified by LC-MS/MS and NMR spectroscopy. Five of the isolated compounds present in A. brasiliana tissues were also detected to be synthesized by endophytic bacteria of the genus Bacillus that were isolated from A. brasiliana. It is speculated that the antibiotic oxylipins from A. brasiliana might derive from bacteria and be involved in an ecological relationship between this plant and its endophytes.

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 Dates: 2014-11-262014-12-082015-02
 Publication Status: Published in print
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 Identifiers: Other: BOL611
DOI: 10.1016/j.phytochem.2014.11.005
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Title: Phytochemistry
  Other : Phyto
Source Genre: Journal
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Publ. Info: Oxford : Pergamon
Pages: - Volume / Issue: 110 Sequence Number: - Start / End Page: 72 - 82 Identifier: ISSN: 0031-9422
CoNE: https://pure.mpg.de/cone/journals/resource/954925433416