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  Compartmental Balloon and BOLD Model

Uludag, K., & Buxton, R. (2005). Compartmental Balloon and BOLD Model. In 13th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2005).

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Uludag, K1, 2, Author           
Buxton, RB, Author
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1Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_2528700              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: The BOLD effect in response to activation is sensitive to the concentration change of deoxy-Hb, which in turn is dependent on CBF, CBV and CMRO2. To relate these quantities, Buxton et al. proposed a balloon model based on the distensibility of the venous vessels. Here, we develop an extension to the current model in modelling the dynamics of deoxy-Hb and CBV not only in the venous part but in all vascular compartments and their individual intra- and extravascular contributions to the BOLD effect. Thus, the new model can predict outcomes of high-resolution imaging and solve apparent contradictions in experimental data.

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 Dates: 2005-05
 Publication Status: Published online
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Title: 13th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2005)
Place of Event: Miami Beach, FL, USA
Start-/End Date: 2005-05-07 - 2005-05-13

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Title: 13th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2005)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 24 Start / End Page: - Identifier: -