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  Interaction of Phalloidin with Actin

Lengsfeld, A., Löw, I., Wieland, T., Dancker, P., & Hasselbach, W. (1974). Interaction of Phalloidin with Actin. Proceedings of the National Academy of Sciences of the United States of America, 71(7), 2803-2807. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/4368830.

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PNAS_71_1974_2803.pdf (Any fulltext), 4MB
 
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 Creators:
Lengsfeld, Anneliese1, Author           
Löw, Irmentraut1, Author           
Wieland, Theodor1, Author           
Dancker, Peter1, Author           
Hasselbach, Wilhelm2, Author           
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1Max Planck Institute for Medical Research, Max Planck Society, ou_1125545              
2Emeritus Group Biophysics, Max Planck Institute for Medical Research, Max Planck Society, ou_1497712              

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Free keywords: toxin; cyclic peptide; liver cell actin; cytochalasin B; microfilaments;
 Abstract: Phalloidin, a toxic bicyclic peptide of rapid action from the toadstool, Amanita phalloides, gives rise to polymerization of G-actin to filamentous structures (Ph-actin) in a medium of low ionic strength. Ph-actin closely resembles the microfilaments found in liver membrane fractions (Ph-filaments) after in vivo or in vitro poisoning. Both phalloidin induced filaments are resistant to 0.6 M KI in contrast to F-actin, and become decorated by heavy meromyosin. After preincubation with cytochalasin B significantly fewer actin filaments are observed.

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Language(s): eng - English
 Dates: 1974-04-101974-07-01
 Publication Status: Issued
 Pages: 5
 Publishing info: -
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Title: Proceedings of the National Academy of Sciences of the United States of America
  Other : Proceedings of the National Academy of Sciences of the USA
  Other : Proc. Acad. Sci. USA
  Other : Proc. Acad. Sci. U.S.A.
  Abbreviation : PNAS
Source Genre: Journal
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Publ. Info: Washington, D.C. : National Academy of Sciences
Pages: - Volume / Issue: 71 (7) Sequence Number: - Start / End Page: 2803 - 2807 Identifier: ISSN: 0027-8424
CoNE: https://pure.mpg.de/cone/journals/resource/954925427230