Increased titer and reduced lactate accumulation in recombinant retrovirus 
production through the down-regulation of HIF1 and PDK

Rodrigues, A. F.; Guerreiro , M. R.; Formas-Oliveira, A. S.; Fernandes, P.; Blechert, Anne-Kareen; Genzel, Yvonne; Alves, P.M.; Hu , W.S.; Coroadinha, A.S.

doi:10.1002/bit.25691

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Increased titer and reduced lactate accumulation in recombinant retrovirus production through the down-regulation of HIF1 and PDK

Rodrigues, A. F., Guerreiro, M. R., Formas-Oliveira, A. S., Fernandes, P., Blechert, A.-K., Genzel, Y., et al. (2016). Increased titer and reduced lactate accumulation in recombinant retrovirus production through the down-regulation of HIF1 and PDK. Biotechnology and Bioengineering, 113(1), 150-162. doi:10.1002/bit.25691.

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Datensatz-Permalink: https://hdl.handle.net/11858/00-001M-0000-0028-4CF2-A Versions-Permalink: https://hdl.handle.net/11858/00-001M-0000-0029-247A-F

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Urheber:
Rodrigues, A. F.^{1, 2}, Autor
Guerreiro , M. R.^{1, 2}, Autor
Formas-Oliveira, A. S.^{1, 2}, Autor
Fernandes, P.^{1, 2}, Autor
Blechert, Anne-Kareen³, Autor
Genzel, Yvonne³, Autor
Alves, P.M.^{1, 2}, Autor
Hu , W.S.⁴, Autor
Coroadinha, A.S.^{1, 2}, Autor

Affiliations:
1iBET – Instituto de Biologia Experimental e Tecnológica, Oeiras, Portugal, ou_persistent22
2Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Av. da República, Oeiras, Portugal, ou_persistent22
3Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society, ou_1738140
4Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, ou_persistent22