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  Macrovascular contributions to high-resolution balanced SSFP- and GE-EPI-based fMRI at 9.4T evaluated using surface-based cortical depth analyses in human visual cortex

Polimeni, J., Zaretskaya, N., Stelzer, J., Bause, J., Ehses, P., Wald, L., et al. (2017). Macrovascular contributions to high-resolution balanced SSFP- and GE-EPI-based fMRI at 9.4T evaluated using surface-based cortical depth analyses in human visual cortex. Poster presented at 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017), Honolulu, HI, USA.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0000-C497-8 Version Permalink: https://hdl.handle.net/21.11116/0000-0000-F2BA-D
Genre: Poster

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Polimeni, J, Author
Zaretskaya, N1, 2, Author           
Stelzer, J2, 3, Author           
Bause, J2, 3, Author           
Ehses, P2, Author           
Wald, L, Author
Scheffler, K2, 3, Author           
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
2Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
3Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: Several strategies have been proposed for maximizing neuronal specificity of fMRI by utilizing pulse sequences that are primarily sensitive to signal changes within microvasculature. Here we compare the microvascular sensitivity of high-resolution balanced SSFP and gradient-echo EPI at 9.4T using cortical depth analyses within human visual cortex. Because of the large draining vessels lying along the pial surface, the behavior of fMRI signals as a function of cortical depth can provide helpful insights into the vascular contributions. Our preliminary analyses suggest that, for the protocols used here, both balanced SSFP and EPI show similar cortical depth profiles of BOLD responses.

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 Dates: 2017-04-27
 Publication Status: Issued
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 Identifiers: BibTex Citekey: PolimeniZSBEWS2017
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Title: 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017)
Place of Event: Honolulu, HI, USA
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Title: 25th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2017)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 5255 Start / End Page: - Identifier: -