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  Multiline balanced SSFP for rapid functional imaging at ultrahigh field

Ehses, P., & Scheffler, K. (2018). Multiline balanced SSFP for rapid functional imaging at ultrahigh field. Magnetic Resonance in Medicine, 79(2), 994-1000. doi:10.1002/mrm.26761.

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Ehses, P1, Author           
Scheffler, K1, 2, Author           
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1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: Purpose The goal of this study is to develop and evaluate a multiline balanced steady-state free-precession (bSSFP) sequence for passband functional MRI at ultrahigh field. Methods Passband bSSFP functional MRI experiments using a visual task were performed on a 9.4 T system with echo trains ranging from one up to seven echoes. We analyze the acquisition efficiency, temporal and thermal signal-to-noise ratio, as well as the observed blood oxygen–level-dependent (BOLD) signal changes. Results With increasing repetition time and echo train length, the BOLD-related signal change as well as the thermal and temporal noise were improved. Activation patterns and signal changes were stable and reproducible across subjects. Conclusions We propose a multiline bSSFP for functional BOLD imaging that approaches the speed of echo-planar imaging and that shows an increased BOLD sensitivity compared with single-line bSSFP.

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 Dates: 2018-02
 Publication Status: Issued
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 Identifiers: DOI: 10.1002/mrm.26761
BibTex Citekey: EhsesS2017
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Title: Magnetic Resonance in Medicine
Source Genre: Journal
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Pages: - Volume / Issue: 79 (2) Sequence Number: - Start / End Page: 994 - 1000 Identifier: -