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  Noradrenergic locus coeruleus ensembles fire at distinct times to evoke different cortical states in rat prefrontal cortex

Noei, S., Zouridis, I., Logothetis, N., Panzeri, S., & Totah, N. (2020). Noradrenergic locus coeruleus ensembles fire at distinct times to evoke different cortical states in rat prefrontal cortex. In J. Pezaris, & N. Hatsopoulos (Eds.), AREADNE 2020: Research in Encoding and Decoding of Neural Ensembles (pp. 94). Cambridge, MA, USA: The AREADNE Foundation.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0007-987F-0 Version Permalink: https://hdl.handle.net/21.11116/0000-0007-9880-C
Genre: Meeting Abstract

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http://areadne.org/2020/pezaris-hatsopoulos-2020-areadne.pdf (Abstract)
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 Creators:
Noei, S, Author
Zouridis, I1, 2, Author           
Logothetis, NK1, 2, Author           
Panzeri, S, Author           
Totah, NK1, 2, Author           
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: The Locus Coeruleus (LC), a noradrenergic brain stem nucleus projecting throughout the forebrain,
is thought to act as an undifferentiated state controller across all forebrain targets because
LC neurons spike synchronously [1, 2]. However, recent work demonstrated ensembles
in the LC and therefore made targeted neuromodulation a possibility [3]. This recent study
used graph theory to reveal a static snapshot of LC ensembles. In order to now demonstrate
that LC ensembles cause targeted neuromodulation, it is necessary to resolve LC ensemble
dynamics over time in relation to ongoing cortical states.

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 Dates: 2020-06
 Publication Status: Published online
 Pages: -
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 Rev. Type: -
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Title: AREADNE 2020: Research in Encoding and Decoding of Neural Ensembles
Place of Event: Santorini, Greece
Start-/End Date: 2020-06-16 - 2020-06-20

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Title: AREADNE 2020: Research in Encoding and Decoding of Neural Ensembles
Source Genre: Proceedings
 Creator(s):
Pezaris, JS, Editor
Hatsopoulos, NG, Editor
Affiliations:
-
Publ. Info: Cambridge, MA, USA : The AREADNE Foundation
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 94 Identifier: ISSN: 2155-3203