ausblenden:
Schlagwörter:
-
Zusammenfassung:
NMR characterization of many proteins is limited by low expression, hurdles for deuteration, and poor sample homogeneity. We introduce a set of high-dimensionality proton-detected experiments developed for unambiguous resonance assignments of such proteins, which we could successfully apply to a 1-mg amount of non-deuterated Tau paired helical filaments.
