English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
 
 
DownloadE-Mail
 Local TagsRelease HistoryDetailsSummary
  Adaptation of nanoarrays for the study of α-synuclein aggregation - preliminary results

Dietrich, H. R. C., van den Doel, R. L., Hoyer, W., van Oel, W., Lung, G. L., Garini, Y., et al. (2005). Adaptation of nanoarrays for the study of α-synuclein aggregation - preliminary results. In D. Nicolau (Ed.), Imaging, manipulation, and analysis of biomolecules and cells: fundamentals and applications III (pp. 395-402). Bellingham, Wash.: Society of Photo Optical Instrumentation Engineers.

Item is

 

show all hide all

Basic

show hide
Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0012-E9F4-6 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0027-DAFA-7
Genre: Book Chapter

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Dietrich, H. R. C., Author
van den Doel, R. L., Author
Hoyer, W.1, Author           
van Oel, W., Author
Lung, G. L., Author
Garini, Y., Author
Jovin, T. M.1, Author           
Young, I. T., Author
Affiliations:
1Department of Molecular Biology, MPI for biophysical chemistry, Max Planck Society, ou_578628              

Content

show
hide
Free keywords: Nanoarrays; High Throughput Screening; Evaporation Control; α-Synuclein; Thioflavin T; Quantitative Fluorescence Microscopy
 Abstract: In previous publications we have shown that we can perform enzymatic reactions in nanoarrays by means of a microarray-reader based on a conventional microscope. In this publication we report on a modification of this system in order to monitor the aggregation kinetics of the natively unfolded protein α-synuclein. We describe the motivation for this development, the problems associated with the miniaturization of the aggregation assay, and the validation of our modifications.

Details

show
hide
Language(s): eng - English
 Dates: 2005-03
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: eDoc: 245856
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Imaging, manipulation, and analysis of biomolecules and cells: fundamentals and applications III
Source Genre: Book
 Creator(s):
Nicolau, D.V., Editor
Affiliations:
-
Publ. Info: Bellingham, Wash. : Society of Photo Optical Instrumentation Engineers
Pages: - Volume / Issue: - Sequence Number: DOI: 10.1117/12.587493 Start / End Page: 395 - 402 Identifier: -

Source 2

show
hide
Title: SPIE Proceedings
Source Genre: Series
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 5699 Sequence Number: - Start / End Page: - Identifier: -