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  Relaxation of hyperpolarized 129Xe in a deflating polymer bag

Möller, H. E., Cleveland, Z. I., & Driehuys, B. (2011). Relaxation of hyperpolarized 129Xe in a deflating polymer bag. Journal of Magnetic Resonance, 212(1), 109-115. doi:10.1016/j.jmr.2011.06.017.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0012-11AF-5 Version Permalink: http://hdl.handle.net/21.11116/0000-0002-EC9E-3
Genre: Journal Article

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 Creators:
Möller, Harald E.1, Author              
Cleveland, Zackary I.2, Author
Driehuys, Bastiaan2, Author
Affiliations:
1Methods and Development Unit Nuclear Magnetic Resonance, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634558              
2Department of Radiology, Center for In Vivo Microscopy, Center for In Vivo Microscopy, Durham, NC, USA, ou_persistent22              

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Free keywords: Gas-phase relaxation; Hyperpolarized 129Xe; Longitudinal relaxation; Magnetic resonance imaging; Wall relaxation
 Abstract: In magnetic resonance imaging with hyperpolarized (HP) noble gases, data is often acquired during prolonged gas delivery from a storage reservoir. However, little is known about the extent to which relaxation within the reservoir will limit the useful acquisition time. For quantitative characterization, 129Xe relaxation was studied in a bag made of polyvinyl fluoride (Tedlar). Particular emphasis was on wall relaxation, as this mechanism is expected to dominate. The HP 129Xe magnetization dynamics in the deflating bag were accurately described by a model assuming dissolution of Xe in the polymer matrix and dipolar relaxation with neighboring nuclear spins. In particular, the wall relaxation rate changed linearly with the surface-to-volume ratio and exhibited a relaxivity of κ = 0.392 ± 0.008 cm/h, which is in reasonable agreement with κ = 0.331 ± 0.051 cm/h measured in a static Tedlar bag. Estimates for the bulk gas-phase 129Xe relaxation yielded View the MathML sourceT1bulk=2.55±0.22h, which is dominated by intrinsic Xe–Xe relaxation, with small additional contributions from magnetic field inhomogeneities and oxygen-induced relaxation. Calculations based on these findings indicate that relaxation may limit HP 129Xe experiments when slow gas delivery rates are employed as, for example, in mouse imaging or vascular infusion experiments.

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Language(s): eng - English
 Dates: 2011-04-202011-06-172011-06-252011-09
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1016/j.jmr.2011.06.017
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Title: Journal of Magnetic Resonance
Source Genre: Journal
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Publ. Info: San Diego [etc.] : Academic Press
Pages: - Volume / Issue: 212 (1) Sequence Number: - Start / End Page: 109 - 115 Identifier: ISSN: 0022-2364
CoNE: /journals/resource/954922651175_1