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  Non-invasive optical imaging of stroke

Obrig, H., & Steinbrink, J. (2011). Non-invasive optical imaging of stroke. Philosophical Transactions of the Royal Society A, 369(1955), 4470-4494. doi:10.1098/rsta.2011.0252.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0012-2426-8 Version Permalink: http://hdl.handle.net/21.11116/0000-0002-EC8E-5
Genre: Journal Article

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 Creators:
Obrig, Hellmuth1, Author              
Steinbrink, Jens2, Author
Affiliations:
1Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
2External Organizations, ou_persistent22              

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Free keywords: stroke; near-infrared spectroscopy; cerebral perfusion; non-invasive; optical imaging; autoregulation
 Abstract: The acute onset of a neurological deficit is the key clinical feature of stroke. In most cases, however, pathophysiological changes in the cerebral vasculature precede the event, often by many years. Persisting neurological deficits may also require long-term rehabilitation. Hence, stroke may be considered a chronic disease, and diagnostic and therapeutic efforts must include identification of specific risk factors, and the monitoring of and interventions in the acute and subacute stages, and should aim at a pathophysiologically based approach to optimize the rehabilitative effort. Non-invasive optical techniques have been experimentally used in all three stages of the disease and may complement the established diagnostic and monitoring tools. Here, we provide an overview of studies using the methodology in the context of stroke, and we sketch perspectives of how they may be integrated into the assessment of the highly dynamic pathophysiological processes during the acute and subacute stages of the disease and also during rehabilitation and (secondary) prevention of stroke.

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Language(s): eng - English
 Dates: 2011-11-282011-11-28
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1098/rsta.2011.0252
 Degree: -

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Title: Philosophical Transactions of the Royal Society A
  Other : Phil. Trans. R. Soc. A
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 369 (1955) Sequence Number: - Start / End Page: 4470 - 4494 Identifier: ISSN: 1364-503X
CoNE: https://pure.mpg.de/cone/journals/resource/954928604111_3