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  A mechanistic account of value computation in the human brain

Philiastides, M. G., Biele, G., & Heekeren, H. R. (2010). A mechanistic account of value computation in the human brain. Proceedings of the National Academy of Sciences of the United States of America, 107(20), 9430-9435. doi:10.1073/pnas.1001732107.

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https://doi.org/10.1073/pnas.1001732107 (Publisher version)
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OA-Status:
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 Creators:
Philiastides, Marios G.1, 2, Author
Biele, Guido1, 2, Author
Heekeren, Hauke R.1, 2, 3, Author           
Affiliations:
1Max Planck Institute for Human Development, Berlin, Germany, ou_persistent22              
2MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634548              
3Department of Education and Psychology, Freie Universität Berlin, Germany, ou_persistent22              

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Free keywords: Decision making; Difference comparator; Functional MRI; Probabilistic evidence; Value
 Abstract: To make decisions based on the value of different options, we often have to combine different sources of probabilistic evidence. For example, when shopping for strawberries on a fruit stand, one uses their color and size to infer - with some uncertainty - which strawberries taste best. Despite much progress in understanding the neural underpinnings of value-based decision making in humans, it remains unclear how the brain represents different sources of probabilistic evidence and how they are used to compute value signals needed to drive the decision. Here, we use a visual probabilistic categorization task to show that regions in ventral temporal cortex encode probabilistic evidence for different decision alternatives, while ventromedial prefrontal cortex integrates information from these regions into a value signal using a difference-based comparator operation.

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Language(s): eng - English
 Dates: 2010-05
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1073/pnas.1001732107
PMID: 20439711
PMC: PMC2889112
 Degree: -

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Project name : -
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Funding program : Emmy Noether Programme
Funding organization : German Research Foundation (DFG)
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Grant ID : -
Funding program : -
Funding organization : Max Planck Society (MPG)

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Title: Proceedings of the National Academy of Sciences of the United States of America
  Other : Proc. Natl. Acad. Sci. U. S. A.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: National Academy of Sciences
Pages: - Volume / Issue: 107 (20) Sequence Number: - Start / End Page: 9430 - 9435 Identifier: ISSN: 0027-8424
CoNE: https://pure.mpg.de/cone/journals/resource/954925427230