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Free keywords:
chemokine receptors; defence suppression; molecular docking; molecular pathogenesis; plant-microbe interactions
Abstract:
Human diseases like AIDS, malaria, and pneumonia are caused by pathogens that corrupt host chemokine G-protein coupled receptors for molecular docking. Comparatively, little is known about plant host factors that are required for pathogenesis and that may serve as receptors for the entry of pathogenic microbes. Here, we review potential analogies between human chemokine receptors and the plant seven-transmembrane MLO protein, a candidate serving a dual role as docking molecule and defence modulator for the phytopathogenic powdery mildew fungus. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
